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ISO-1 (Synonyms: MIF Antagonist)

Cat. No.: HY-16692 Purity: 99.64%
Handling Instructions

ISO-1 is a macrophage migration inhibitory factor (MIF) antagonist with an IC50 of 7 μM.

For research use only. We do not sell to patients.

ISO-1 Chemical Structure

ISO-1 Chemical Structure

CAS No. : 478336-92-4

Size Price Stock Quantity
Free Sample (0.5-1 mg)   Apply now  
10 mM * 1 mL in DMSO USD 112 In-stock
Estimated Time of Arrival: December 31
5 mg USD 102 In-stock
Estimated Time of Arrival: December 31
10 mg USD 168 In-stock
Estimated Time of Arrival: December 31
50 mg USD 706 In-stock
Estimated Time of Arrival: December 31
100 mg   Get quote  
200 mg   Get quote  

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Customer Review

Based on 3 publication(s) in Google Scholar

Top Publications Citing Use of Products

    ISO-1 purchased from MCE. Usage Cited in: J Neuroinflammation. 2018 Oct 19;15(1):291.

    ISO-1 treatment partially recovers PCN033- or RS218-mediated downregulation of the tight junction proteins ZO-1 and occludin.

    ISO-1 purchased from MCE. Usage Cited in: J Neuroinflammation. 2018 Oct 19;15(1):291.

    ISO-1 treatment partially recovers PCN033- or RS218-mediated downregulation of the tight junction proteins ZO-1 and occludin.
    • Biological Activity

    • Technical Information

    • Purity & Documentation

    • References

    Description

    ISO-1 is a macrophage migration inhibitory factor (MIF) antagonist with an IC50 of 7 μM.

    Storage
    Powder -20°C 3 years
      4°C 2 years
    In solvent -80°C 6 months
      -20°C 1 month
    Solvent & Solubility
    In Vitro: 

    DMSO : ≥ 36 mg/mL (153.04 mM)

    *"≥" means soluble, but saturation unknown.

    Preparing
    Stock Solutions
    Concentration Solvent Mass 1 mg 5 mg 10 mg
    1 mM 4.2510 mL 21.2549 mL 42.5098 mL
    5 mM 0.8502 mL 4.2510 mL 8.5020 mL
    10 mM 0.4251 mL 2.1255 mL 4.2510 mL
    *Please refer to the solubility information to select the appropriate solvent.
    References
    Molecular Weight

    235.24

    Formula

    C₁₂H₁₃NO₄

    CAS No.

    478336-92-4

    SMILES

    O=C(OC)CC1ON=C(C(C=C2)=CC=C2O)C1

    Shipping

    Room temperature in continental US; may vary elsewhere

    Purity: 99.64%

    • Molarity Calculator

    • Dilution Calculator

    The molarity calculator equation

    Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

    Mass   Concentration   Volume   Molecular Weight *
    = × ×

    The dilution calculator equation

    Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

    This equation is commonly abbreviated as: C1V1 = C2V2

    Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
    × = ×
    C1   V1   C2   V2

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    Inquiry Information

    Product Name:
    ISO-1
    Cat. No.:
    HY-16692
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    ISO-1

    Cat. No.: HY-16692