1. Protein Tyrosine Kinase/RTK
  2. Syk
  3. Fostamatinib disodium hexahydrate

Fostamatinib disodium hexahydrate (Synonyms: R788 disodium hexahydrate)

Cat. No.: HY-13038B Purity: 99.92%
Handling Instructions

Fostamatinib disodium hexahydrate (R788 disodium hexahydrate), a prodrug of the active metabolite R406, is a potent Syk inhibitor with IC50 of 41 nM.

For research use only. We do not sell to patients.

Fostamatinib disodium hexahydrate Chemical Structure

Fostamatinib disodium hexahydrate Chemical Structure

CAS No. : 914295-16-2

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10 mM * 1 mL in DMSO USD 155 In-stock
Estimated Time of Arrival: December 31
5 mg USD 96 In-stock
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10 mg USD 144 In-stock
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50 mg USD 432 In-stock
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100 mg USD 708 In-stock
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Customer Review

Based on 5 publication(s) in Google Scholar

Other Forms of Fostamatinib disodium hexahydrate:

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  • Biological Activity

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Description

Fostamatinib disodium hexahydrate (R788 disodium hexahydrate), a prodrug of the active metabolite R406, is a potent Syk inhibitor with IC50 of 41 nM.

IC50 & Target

Syk

Clinical Trial
Molecular Weight

732.51

Formula

C₂₃H₃₆FN₆Na₂O₁₅P

CAS No.

914295-16-2

SMILES

COC1=CC(NC2=NC=C(C(NC3=NC(N4COP(O[Na])(O[Na])=O)=C(C=C3)OC(C)(C)C4=O)=N2)F)=CC(OC)=C1OC.O.O.O.O.O.O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 31.81 mg/mL (43.43 mM; Need ultrasonic)

H2O : 2 mg/mL (2.73 mM; ultrasonic and warming and heat to 60°C)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.3652 mL 6.8258 mL 13.6517 mL
5 mM 0.2730 mL 1.3652 mL 2.7303 mL
10 mM 0.1365 mL 0.6826 mL 1.3652 mL
*Please refer to the solubility information to select the appropriate solvent.
References

Purity: 99.92%

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Keywords:

Fostamatinib disodium hexahydrateR788 disodium hexahydrateSykSpleen tyrosine kinaseInhibitorinhibitorinhibit

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Product Name:
Fostamatinib disodium hexahydrate
Cat. No.:
HY-13038B
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