Others

(S)-2-Aminobutyramide-d₃ hydrochloride is the deuterium labeled (S)-2-Aminobutyramide hydrochloride (HY-79491). (S)-2-aminobutyramide hydrochloride is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

FAAH-IN-2 (Standard) is the analytical standard of FAAH-IN-2. This product is intended for research and analytical applications. FAAH-IN-2 (O-Desmorpholinopropyl Gefitinib) is an inhibitor of FAAH. FAAH-IN-2 is a metabolite of Gefitinib (HY-50895).

Solifenacin impurity 4 ((1R,3S)-Solifenacin) is an impurity of Solifenacin.

Fmoc-Aib-OH-d₃ is the deuterium labeled Fmoc-Aib-OH (HY-79648). Fmoc-Aib-OH is an alanine derivative.

1-Bromo-4-(bromomethyl)benzene-d₆ is the deuterium labeled 1-Bromo-4-(bromomethyl)benzene.

cis-Tadalafil-d₃ is the deuterium labeled cis-Tadalafil[1].

cis-ent-Tadalafil-d₃ is the deuterium labeled cis-ent-Tadalafil[1].

Ramelteon-d₃ (TAK-375-d₃) is a deuterium-labelled Ramelteon (HY-A0014). Ramelteon is a potent, highly selective, and orally active agonist of MT1/MT2 with K_i values of 14 and 112 pM, respectively. Ramelteon has the potential for the research of insomnia.

Methacholine (chloride) (Standard) is the analytical standard of Methacholine (chloride). This product is intended for research and analytical applications. Methacholine (Acetyl-β-methylcholine) choride is a potent muscarinic-3 (M3) agonist. Methacholine choride acts directly on acetylcholine receptors on smooth muscle causing bronchoconstriction and airway narrowing. Methacholine choride shows a high sensitivity to identify bronchial hyperresponsiveness (BHR). Methacholine choride can be used to measure airway hyperresponsiveness (AHR) as a diagnostic aid in the assessment of individuals with asthma-like symptoms and normal resting expiratory flow rates.

Trimethyl phosphate (Standard) is the analytical standard of Trimethyl phosphate (HY-A0108A). This product is intended for research and analytical applications. Trimethyl phosphate is a methylating agent. Trimethyl phosphate transfers methyl groups to aliphatic alcohols, phenols, and amines.

Thiothixene is a typical antipsychotic. It selectively binds to dopamine D2 over D1, D3, and D4 receptors (Kis=0.417, 338, 186.2, and 363.1 nM, respectively). Thiothixene also binds to various serotonin (5-HT), histamine H1, α1- and α2-adrenergic, muscarinic acetylcholine, and sigma receptors (Kis=15-5,754 nM) as well as the dopamine, norepinephrine, and serotonin transporters (Kis=3.16-30 μM). In vivo, thiothixene reduces spontaneous and amphetamine-induced locomotor activity in rats. It enhances latent inhibition, as measured by a decreased lick latency in response to light and foot shock stimuli, which is a measure of selective attention in rats.3 Thiothixene also increases competitive behavior in submissive mice, indicating antidepressant-like behavior.

Hydroxystilbamidine diisethionate, a dye capable of binding to both DNA and RNA, is a powerful inhibitor of cellular ribonucleases. Hydroxystilbamidine diisethionate is a retrograde fluorescent tracer and histochemical stain.

(E)-Fluvoxamine-d₄ (maleate) is the deuterium labeled (E)-Fluvoxamine maleate[1].

Levetiracetam impurity 5 is an impurity of Levetiracetam.

Daptomycin-d₅ (LY146032-d₅) is the deuterium labeled Daptomycin (HY-B0108). Daptomycin is a lipopeptide antibiotic with rapid in vitro bactericidal activity against gram-positive organisms.

Dorzolamide-d₃ hydrochloride is deuterated labeled Dorzolamide hydrochloride (HY-B0109A). Dorzolamide (L671152) hydrochloride is a potent carbonic anhydrase II inhibitor, with IC₅₀ values of 0.18 nM and 600 nM for red blood cell CA-II and CA-I respectively. Dorzolamide possesses anti-tumor activity.

Flucytosine-¹⁵N₂ (5-Fluorocytosine-¹⁵N₂) hydrochloride is the ¹⁵N-labeled Flucytosine hydrochloride (HY-B0139). Flucytosine (5-Fluorocytosine) is an antifungal compound with oral activity. Flucytosine is a widely used cytotoxic drug that, after further metabolism, produces fluorinated ribonucleotides and deoxyribonucleotides, inhibits DNA and protein synthesis, and has multiple effects such as inhibiting candida and candida neoplasm infection and producies cytotoxicity to cancer cells.

Niacinamide ascorbate is a micronutrient with radioprotective properties. Niacinamide ascorbate works as an antioxidant along with vitamin C, vitamin E and other compounds to mitigate the risks associated with exposure to ionizing radiation. Niacinamide ascorbate helps reduce the likelihood of radiation-induced diseases such as acute leukemia, breast cancer, thyroid cancer and mutations, thereby protecting the human body from the harmful effects of radiation.

Guanidine-¹³C,¹⁵N₃ hydrochloride (Guanidinium-¹³C,¹⁵N₃ (chloride)) is the ¹⁵N, ¹³C-labeled Guanidine hydrochloride (HY-B0178A). Guanidine hydrochloride is a strong protein denaturant. Guanidine hydrochloride causes proteins to assume a random coil conformation.

Azathioprine-d₃ (BW 57-322-d₃) is the deuterium labeled Azathioprine (HY-B0256). Azathioprine (BW 57-322) is an orally active immunosuppressive agent. Azathioprine can be converted in vivo to the active metabolite 6-mercaptopurine (6-MP). Azathioprine has myelosuppressive effects and induces apoptosis.