Methacholine chloride (Standard)
Methacholine (chloride) (Standard) is the analytical standard of Methacholine (chloride). This product is intended for research and analytical applications. Methacholine (Acetyl-β-methylcholine) choride is a potent muscarinic-3 (M3) agonist. Methacholine choride acts directly on acetylcholine receptors on smooth muscle causing bronchoconstriction and airway narrowing. Methacholine choride shows a high sensitivity to identify bronchial hyperresponsiveness (BHR). Methacholine choride can be used to measure airway hyperresponsiveness (AHR) as a diagnostic aid in the assessment of individuals with asthma-like symptoms and normal resting expiratory flow rates.
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- Pureté : 95%
- CAS No.: 62-51-1
- Formule: C8H18ClNO2
- Masse moléculaire:195.69
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Product Information
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Chemical Information
- Pureté et documentation
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Help & FAQs
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HY-A0083
Methacholine chlorideMuscarinic-3 Agonist -
HY-B0726
Pilocarpine HydrochloridemAChR Agonist -
HY-101086
Acetylcholine iodideMuscarinic Receptor Modulator -
HY-B0489
Arecoline hydrobromidenAChR/mAChR Agonist -
HY-N0175
CytisiniclinenAChR Agonist -
HY-N0175R
Cytisinicline (Standard)nAChR Agonist -
HY-101086R
Acetylcholine iodide (Standard)Muscarinic Receptor Modulator -
HY-B0489R
Arecoline hydrobromide (Standard)nAChR/mAChR Agonist -
HY-B0726R
Pilocarpine Hydrochloride (Standard)mAChR Agonist
Product Information
Information
Application
The compound is the grade of analytical standard, which is the reference standard supplied assay. It is commonly used in qualitative, quantitative and methodological research experiments in HPLC, GC and MS.
Chemical Information
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CAS No. 62-51-1
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Masse moléculaire 195.69
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Formule C8H18ClNO2
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SMILES
CC(OC(C)=O)C[N+](C)(C)C.[Cl-]
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Synonyms
Acetyl-β-methylcholine chloride (Standard)
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
[1]. Cohen J, et al. Relationship between airway responsiveness to neurokinin A and methacholine in asthma. Pulm Pharmacol Ther. 2005;18(3):171-176. [Content Brief]
[2]. Anderson SD, et al. Comparison of mannitol and methacholine to predict exercise-induced bronchoconstriction and a clinical diagnosis of asthma. Respir Res. 2009;10(1):4. Published 2009 Jan 23. [Content Brief]
[3]. Cockcroft DW. Methacholine challenge methods. Chest. 2008;134(4):678-680. [Content Brief]
[4]. Kabara S, et al. Differential effects of thiopental on methacholine- and serotonin-induced bronchoconstriction in dogs. Br J Anaesth. 2003 Sep;91(3):379-84. [Content Brief]
[5]. Folkerts G, et al. Bradykinin causes inhibition of methacholine-induced bronchoconstriction in vivo in mice. Naunyn Schmiedebergs Arch Pharmacol. 2001 Jul;364(1):53-8. [Content Brief]
[6]. Vitorasso RL, et al. Methacholine dose response curve and acceptability criteria of respiratory mechanics modeling. Exp Lung Res. 2020 Feb-Mar;46(1-2):23-31. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Methacholine chloride (Standard) Related Classifications
HY-A0083R Related Classifications
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