184475-71-6
184475-71-6
Chemical Structure
FAAH-IN-2
Synonym(s): O-Desmorpholinopropyl Gefitinib
- CAS No.: 184475-71-6
- Formula:C15H11ClFN3O2
- Molecular Weight:319.72
IUPAC Name: 4-((3-chloro-4-fluorophenyl)amino)-7-methoxyquinazolin-6-ol
InChIKey: JLVTVCRXFMLUIF-UHFFFAOYSA-N
SMILES: OC1=CC2=C(NC3=CC=C(F)C(Cl)=C3)N=CN=C2C=C1OC
Biological Activity: FAAH-IN-2 (O-Desmorpholinopropyl Gefitinib) is an inhibitor of FAAH. FAAH-IN-2 is a metabolite of Gefitinib (HY-50895)[1][2][3].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
|
FAAH-IN-2 | 98.21% | FAAH-IN-2 (O-Desmorpholinopropyl Gefitinib) is an inhibitor of FAAH. FAAH-IN-2 is a metabolite of Gefitinib (HY-50895). | ||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
|
|
FAAH-IN-2 (Standard) | ≥98% | FAAH-IN-2 (Standard) is the analytical standard of FAAH-IN-2. This product is intended for research and analytical applications. FAAH-IN-2 (O-Desmorpholinopropyl Gefitinib) is an inhibitor of FAAH. FAAH-IN-2 is a metabolite of Gefitinib (HY-50895). | ||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
References
- [1]. Olivier Dasse, et al. Carbamates therapeutic release agents as amidase inhibitors. WO/2008/100977A2.
- [2]. Zhu Y, et al. FAAH served a key membrane-anchoring and stabilizing role for NLRP3 protein independently of the endocannabinoid system. Cell Death Differ. 2023 Jan;30(1):168-183. [Content Brief]
- [3]. Kumawat S, et al. Dearomative Difluoromethylation of N-Heterocycles and Pharmaceuticals with Bromo(difluoro)acetic Acid. J Org Chem. 2025 Jul 18;90(28):9826-9844. [Content Brief]
