Others

N-Methylthalidomide-Pip-NHBoc is an E3 ligase ligand-linker conjugate that incorporates the CRBN ligand and a linker. N-Methylthalidomide-Pip-NHBoc can be used to synthesize LLC0424N (HY-185557) .

F6OM, a nonionic fluorinated octyl maltoside derivative, is a surfactant. F6OM readily interacts with and completely solubilizes phospholipid vesicles via a heterogeneous solubilization mechanism, without compromising membrane order at subsolubilizing concentrations. F6OM promotes bilayer insertion of an integral membrane enzyme in the absence of micelles to support functional refolding of integral membrane proteins. F6OM can be used for membrane-protein applications.

ATM ligand-1 is an ATM ligand that can be used for the synthesis of PROTACs, such as PROTAC ATM degrader-1 (HY-158345).

Anionic Liposomes (DOPG, 10mM) is a Phosphatidylglycerol (PG)-based-100% DOPG formulation. Anionic Liposomes (DOPG, 10mM) can be used for drug delivery and lipid-protein interactions.

4-(Cyclohexylbuta-1,3-diyn-1-yl)benzoic acid is a Hyt hydrophobic group. 4-(Cyclohexylbuta-1,3-diyn-1-yl)benzoic acid can be used in the synthesis of PARP1 degrader 1 (HY-180276).

N,3-BisBoc-L-Histidine is a Hyt hydrophobic group. N,3-BisBoc-L-Histidine can be used in the synthesis of BCR-ABL degrader 1 (HY-180798).

ST41 is a conjugate compound having three saccharide ligands and modified phosphate groups within the saccharide portion. ST41 can be used for nucleotide modification and targeted delivery.

2',5'-Dideoxy-3'-ATP is an adenylate cyclase inhibitor. 2',5'-Dideoxy-3'-ATP exerts linear noncompetitive inhibition via binding to the distinct P-site. 2',5'-Dideoxy-3'-ATP binds and stabilizes the dimeric form of Mycobacterium avium adenylyl cyclase Ma1120 to inhibit activity.

W19-LNP is a lipid nanoparticle formulated with a Ugi-reaction-derived ionizable lipid (W19). W19-LNP demonstrates highly selective mRNA delivery to the spleen in female BALB/c mice upon intravenous administration. W19-LNP can be used for the research of mRNA-based vaccine delivery, immune cell reprogramming, and gene-engineered cell preparation.

DBCO2-PEG24 is a non-targeting bivalent DBCO-functionalized shielding agent with a PEG24 spacer, which can be used as a surface shielding control. DBCO2-PEG24 binds to the surface of lipid oligomer-modified siRNA lipopolymer nanoparticles via copper-free click reaction (SPAAC).

IRF4 ligand-1 is an IRF4 ligand that can be used for the synthesis of PROTACs, such as dIRF4-2 (HY-185697).

1-Naphthaleneacetic acid (Standard) is the analytical standard of 1-Naphthaleneacetic acid. This product is intended for research and analytical applications. 1-Naphthaleneacetic acid (1-Naphthylacetic acid), a auxin, can promote plant growth. 1-Naphthaleneacetic acid is also an inhibitor of PLA2, with an IC50 of 13.16 μM.

DBCO-PEG4-bis-PEG3-methyltetrazine is a branched PEG linker consisting of a DBCO group, which reacts with azides via click chemistry, and two methyltetrazine groups, which swiftly react with TCO via click chemistry. Branched design elevates ADC payload capacity.

NSC-41589 is N-[2-(methylsulfanyl) phenyl]acetamide.

ETE-S trimer is a conjugated trimer that undergoes polymerization under the action of plant cell wall peroxidases, forming an ion-electron hybrid conductive polymer suitable for bio-hybrid supercapacitors.

PEDA is a chemical intermediate. PEDA can participate in the CuAAC reaction to synthesize ethylenediamine analogs including Biot-EDA, Cy3-EDA, EDA-AG and EDA-m⁷Gp3G, which are used for RNA modification.

DOTA-tris (t-Bu) ester-PEG3-C2-amine (Compound 9) is a conjugate of DOTA-based chelator and linker, bearing tris (t-Bu) ester and PEG3-C2-amine functional groups. DOTA-tris (t-Bu) ester-PEG3-C2-amine can be conjugated to payloads via bioorthogonal click chemistry for targeted delivery.

4-Hydroxy-L-arginine is a arginine derivative.

(S,S)-Reboxetine-OH is a phenol compound. (S,S)-Reboxetine-OH can be used to synthesize norepinephrine transporter ligand.

Mal-(1R,2S,3R,4S)-himic acid-alkyne is a trifunctional click chemistry scaffold containing complementary functionalities for copper catalyzed azide-alkyne (CuAAC), thiol-Michael addition, and inverse electron demand Diels-Alder (iEDDA) click reactions.