2. PROTAC Protein Tyrosine Kinase/RTK
  3. HyT Bcr-Abl
  4. BCR-ABL degrader 1

BCR-ABL degrader 1 (Compound 23) is a HyT-based BCR-ABL degrader with a DC50 of 19.9 μM. BCR-ABL degrader 1 can be used in the research of chronic myeloid leukemia.

For research use only. We do not sell to patients.

BCR-ABL degrader 1

BCR-ABL degrader 1 Chemical Structure

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BCR-ABL degrader 1 Related Antibodies

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Description

BCR-ABL degrader 1 (Compound 23) is a HyT-based BCR-ABL degrader with a DC50 of 19.9 μM. BCR-ABL degrader 1 can be used in the research of chronic myeloid leukemia[1].

IC50 & Target

DC50: 19.9 μM (BCR-ABL)[1]
Molecular Weight

683.68

Formula

C33H36F3N7O6
SMILES

O=C(N1C(C[C@H](NC(OC(C)(C)C)=O)C(NC2=CC=CC(C3=NC=NC(NC4=CC=C(OC(F)(F)F)C=C4)=C3)=C2)=O)=CN=C1)OC(C)(C)C
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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BCR-ABL degrader 1 Related Classifications

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

BCR-ABL degrader 1HyTBcr-AblHydrophobie taggingchronic myeloid leukemiaInhibitorinhibitorinhibit

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BCR-ABL degrader 1
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HY-180798
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