2. Signaling Pathways
  3. Protein Tyrosine Kinase/RTK
  4. Bcr-Abl
  5. Bcr-Abl Isoform
  6. Bcr-Abl Degrader

Bcr-Abl Degrader

Bcr-Abl Degraders (4):

Cat. No. Product Name Effect Purity
  • HY-152036A
    SIAIS100 TFA
    		Degrader
    SIAIS100 TFA is a potent BCR-ABL PROTAC degrader with an DC50 value of 2.7 nM. SIAIS100 TFA can be used to research chronic myeloid leukemia (CML).
  • HY-153415
    PROTAC BCR-ABL Degrader-1
    		Degrader 98.09%
    PROTAC BCR-ABL Degrader-1 (compound PROTAC 1) is a PROTAC with a 2-oxoethyl linker. PROTAC BCR-ABL Degrader-1 induces Bcr-Abl degradation in a ubiquitinproteasom-dependent manner. PROTAC BCR-ABL Degrader-1 exhibits antiproliferative activity against K562 cells, and has the potential to study cancer.
  • HY-152036
    SIAIS100
    		Degrader
    SIAIS100 is a potent BCR-ABL PROTAC degrader with an DC50 value of 2.7 nM. SIAIS100 can be used to research chronic myeloid leukemia (CML).
  • HY-153582
    ML 2-23
    		Degrader
    ML 2-23 is a potent PROTAC BCR-ABL degrader. ML 2-23 is selectively degrade BCR-ABL in a proteasome-dependent manner in leukemia cells.