3037776-67-0

Arg-PEG1-Dasa Chemical Structure
3037776-67-0

Chemical Structure

Arg-PEG1-Dasa

  • CAS No.: 3037776-67-0
  • Formula:C33H47ClN12O5S
  • Molecular Weight:759.32

InChIKey: UMCJYQURSZMMCC-DEOSSOPVSA-N

SMILES: CC1=NC(NC2=NC=C(C(NC3=C(C=CC=C3Cl)C)=O)S2)=CC(N4CCN(CC4)CCOC(CCOCCNC([C@@H](N)CCCNC(N)=N)=O)=O)=N1

Biological Activity: Arg-PEG1-Dasa is a mini-PROTAC targeting BCR-ABL. Arg-PEG1-Dasa induces BCR-ABL degradation (EC50 = 0.85 nM) and shows antiproliferative activity in K562 cells (IC50 = 0.36 nM). Arg-PEG1-Dasa can be used for chronic myeloid leukemia research[1].

Cat. No. Product Name Purity Description Pricing
HY-186016 		Arg-PEG1-Dasa Arg-PEG1-Dasa is a mini-PROTAC targeting BCR-ABL. Arg-PEG1-Dasa induces BCR-ABL degradation (EC50 = 0.85 nM) and shows antiproliferative activity in K562 cells (IC50 = 0.36 nM). Arg-PEG1-Dasa can be used for chronic myeloid leukemia research.
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