N-Methylthalidomide-Pip-NHBoc
N-Methylthalidomide-Pip-NHBoc is an E3 ligase ligand-linker conjugate that incorporates the CRBN ligand and a linker. N-Methylthalidomide-Pip-NHBoc can be used to synthesize LLC0424N (HY-185557) .
For research use only. We do not sell to patients.
- CAS No.: 3061315-50-9
- Formula: C24H30N4O6
- Molecular Weight:470.52
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
All E3 Ligase Ligand-Linker Conjugates Isoforms
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Biological Activity
PROTAC consists of two distinct ligands linked by a linker; one is the ligand of E3 ubiquitin ligase, and the other is the ligand of the target protein. PROTAC selectively degrades target proteins by utilizing the intracellular ubiquitin-proteasome system.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 3061315-50-9
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Molecular Weight 470.52
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Formula C24H30N4O6
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SMILES
O=C(NC1CCN(CC1)C2=CC=C3C(N(C4C(N(C)C(CC4)=O)=O)C(C3=C2)=O)=O)OC(C)(C)C
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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