Others

Fuc (1→2)-Gal(3→1)(C3-amide-C5-biotin)-GalNAc (Compound 81) is a trisaccharide-spacer arm biotin conjugate. Fuc (1→2)-Gal (3→1)(C3-amide-C5-biotin)-GalNAc serves as a research tool in glycobiology.

IQ-R is a novel hypoxia-sensitive fluorescent probe, consisting of an indolequinone unit and a rhodol fluorophore.

5,6-Bis(4-methoxyphenyl)-2,3-diphenylthieno[3,2-b]furan is a herbicide.

Multi-kinase-IN-11 (Compound 1a) is a DFG-out conformation-targeted multi-kinase inhibitor, including SRC, LCK, ABL, PYK2, CSK, HCK, P38 and C-KIT. Multi-kinase-IN-11 serves as a scaffold for the preparation of fluorescently labeled binding probes and affinity matrices.

L-651896 is a compound with anti-inflammatory and antiproliferative activities that inhibits 5-lipoxygenase and cyclooxygenase, thereby reducing the production of leukotrienes and prostaglandins. L-651896 can be used in the study of skin diseases and other inflammatory diseases.

SCH-34826 is an orally active neutral metalloendopeptidase (NEP) inhibitor that inhibits NEP and reduces the degradation of ANF, thereby enhancing its antihypertensive and diuretic effects. SCH-34826 can be used in the research of cardiovascular and renal diseases.

RG-7152 is a tetrazolyl-substituted leukotriene D4 receptor antagonist that can induce peroxisomal β-oxidation and peroxisome bifunctional enzymes (PBEs) in hepatocytes in various animal models. It has been shown to significantly increase PBE levels and β-oxidation activity in rat and mouse liver homogenates, while smaller effects were observed in guinea pigs and monkeys and no effect in dogs. In vitro studies have also shown that it can induce PBEs comparable to clofibric acid, indicating its potential as a peroxisome proliferator.

ZD-6888 hydrochloride (ICI-D 6888 hydrochloride) is an antagonist for angiotensin II, which competitively inhibits the angiotensin II-mediated release of renin, affects the renal structure and function.

2-NAP is a major metabolite of polycyclic aromatic hydrocarbons (PAHs). 2-NAP induces oxidative stress and inflammatory responses, impairs enamel formation, and disrupts oral microbiome balance, increasing the risk of early childhood caries (ECC). 2-NAP is promising for research of development-related diseases such as childhood caries.

S-0509 is a selective CCKB/gastrin receptor antagonist. S-0509 has a strong anti-secretion effect. S-0509 helps prevent the occurrence of duodenal ulcers.

Upenazime is a non-radioactive precursor agent for diagnostic imaging.

AR-13324 analog mesylate is an analog of AR-13324. AR-13324 is an ROCK and norepinephrine transporter (NET) inhibitor.

E-2101 is a novel antispastic agent. E-2101 is a competitive CYP2C19 and CYP2D6 inhibitor with K_i values of 15 and 48 μM, respectively. E-2101 is metabolized by Cytochromes P450 to form monohydroxylated (M1 and M2), dihydroxylated (M3), and N-dealkylated metabolites (M4). E-2101 can be used in the research of skeletal muscle spasm.

UK 357903 is a selective inhibitor for phosphodiesterase 5 (PDE5), with IC₅₀s of 1.7 and 714 nM, for PDE5 and PDE6. UK 357903 exhibits vasodilatory effects on the mesenteric and hindlimb vascular beds, and is potential for ameliorating erectile dysfunction.

UK-371800 is a highly selective PDE5 inhibitor (IC₅₀ = 4.2 nM). UK-371800 has good permeability and is not affected by the efflux of P-glycoprotein.

OT-730 is an innovative selective beta-blocker prodrug designed for research into ocular diseases.

BASF 43915 (Pelretin) is a Phenyl analog.

JNJ-42165279 (dihydrochloride) is aFAAHinhibitor with IC₅₀ of 70 nM and 313 nM for hFAAH and rFAAH, respectively.

(S)-Oxybutynin-d₁₀ (Esoxybutynin-d₁₀) is deuterium labeled (S)-Oxybutynin (Esoxybutyni).

4-Chlorophenoxyacetic acid (sodium) (Standard) is the analytical standard of 4-Chlorophenoxyacetic acid (sodium). This product is intended for research and analytical applications. 4-Chlorophenoxyacetic acid (sodium) (4-CPA (sodium); p-Chlorophenoxyacetic acid (sodium)) is a chlorophenol compound that can act as a plant growth regulator and herbicide. At low concentrations, 4-Chlorophenoxyacetic acid sodium promotes plant growth, while at high concentrations, it inhibits plant growth (especially in dicotyledonous plants). 4-Chlorophenoxyacetic acid (sodium) is a kind of biological materials or organic compounds that are widely used in life science research.