1157857-36-7
Chemical Structure
Multi-kinase-IN-11
- CAS No.: 1157857-36-7
- Formula:C30H24F3N7O2
- Molecular Weight:571.56
IUPAC Name: N-(3-((3-(4-((4-methoxyphenyl)amino)-1,3,5-triazin-2-yl)pyridin-2-yl)amino)-4-methylphenyl)-3-(trifluoromethyl)benzamide
InChIKey: FLZNVZVIUIDCOF-UHFFFAOYSA-N
SMILES: O=C(NC1=CC=C(C(=C1)NC=2N=CC=CC2C=3N=CN=C(N3)NC4=CC=C(OC)C=C4)C)C5=CC=CC(=C5)C(F)(F)F
Biological Activity: Multi-kinase-IN-11 (Compound 1a) is a DFG-out conformation-targeted multi-kinase inhibitor, including SRC, LCK, ABL, PYK2, CSK, HCK, P38 and C-KIT. Multi-kinase-IN-11 serves as a scaffold for the preparation of fluorescently labeled binding probes and affinity matrices[1].
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Multi-kinase-IN-11 | Multi-kinase-IN-11 (Compound 1a) is a DFG-out conformation-targeted multi-kinase inhibitor, including SRC, LCK, ABL, PYK2, CSK, HCK, P38 and C-KIT. Multi-kinase-IN-11 serves as a scaffold for the preparation of fluorescently labeled binding probes and affinity matrices. | |||||||||||||||||||||
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Keywords