247580-98-9
Chemical Structure
UK 357903
- CAS No.: 247580-98-9
- Formula:C27H34N8O5S
- Molecular Weight:582.67
IUPAC Name: 3-ethyl-5-(5-((4-ethylpiperazin-1-yl)sulfonyl)-2-(2-methoxyethoxy)pyridin-3-yl)-2-(pyridin-2-ylmethyl)-2H-pyrazolo[4,3-d]pyrimidin-7(4H)-one
InChIKey: QDPNAMRLQRQPMR-UHFFFAOYSA-N
SMILES: O=C1N=C(C2=C(OCCOC)N=CC(S(=O)(N3CCN(CC3)CC)=O)=C2)NC4=C(CC)N(CC5=NC=CC=C5)N=C41
Biological Activity: UK 357903 is a selective inhibitor for phosphodiesterase 5 (PDE5), with IC50s of 1.7 and 714 nM, for PDE5 and PDE6. UK 357903 exhibits vasodilatory effects on the mesenteric and hindlimb vascular beds, and is potential for ameliorating erectile dysfunction[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
|
UK 357903 | UK 357903 is a selective inhibitor for phosphodiesterase 5 (PDE5), with IC50s of 1.7 and 714 nM, for PDE5 and PDE6. UK 357903 exhibits vasodilatory effects on the mesenteric and hindlimb vascular beds, and is potential for ameliorating erectile dysfunction. | |||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
Keywords
