UK 357903
UK 357903 is a selective inhibitor for phosphodiesterase 5 (PDE5), with IC50s of 1.7 and 714 nM, for PDE5 and PDE6. UK 357903 exhibits vasodilatory effects on the mesenteric and hindlimb vascular beds, and is potential for ameliorating erectile dysfunction.
Para uso exclusivo en investigación. No vendemos a pacientes.
- No. CAS: 247580-98-9
- Fòrmula: C27H34N8O5S
- Peso molecular:582.67
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Almacenamiento:
Please store the product under the recommended conditions in the Certificate of Analysis.
Actividad biológica
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PDE5 1.7 nM (IC50) |
PDE6 714 nM (IC50) |
Chemical Information
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No. CAS 247580-98-9
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Peso molecular 582.67
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Fòrmula C27H34N8O5S
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SMILES
O=C1N=C(C2=C(OCCOC)N=CC(S(=O)(N3CCN(CC3)CC)=O)=C2)NC4=C(CC)N(CC5=NC=CC=C5)N=C41
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureza y Documentación
Referencias
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)