247582-13-4
247582-13-4
Chemical Structure
UK-371800
- CAS No.: 247582-13-4
- Formula:C23H33N7O5S
- Molecular Weight:519.62
IUPAC Name: (R)-3-ethyl-5-(5-((4-ethylpiperazin-1-yl)sulfonyl)-2-((1-methoxypropan-2-yl)oxy)pyridin-3-yl)-2-methyl-2,4-dihydro-7H-pyrazolo[4,3-d]pyrimidin-7-one
InChIKey: WKISNFXGTYNPOO-OAHLLOKOSA-N
SMILES: O=C1C2=NN(C)C(CC)=C2NC(C3=CC(S(=O)(N4CCN(CC)CC4)=O)=CN=C3O[C@H](C)COC)=N1
Biological Activity: UK-371800 is a highly selective PDE5 inhibitor (IC50 = 4.2 nM). UK-371800 has good permeability and is not affected by the efflux of P-glycoprotein[1].
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UK-371800 | UK-371800 is a highly selective PDE5 inhibitor (IC50 = 4.2 nM). UK-371800 has good permeability and is not affected by the efflux of P-glycoprotein. | |||||||||||||||||||||
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References
Keywords
