1. GPCR/G Protein
    Neuronal Signaling
  2. Somatostatin Receptor
  3. SSTR5 antagonist 1

SSTR5 antagonist 1 

Cat. No.: HY-102037 Purity: 99.69%
Handling Instructions

SSTR5 antagonist 1 is a potent, selective, and orally available somatostatin receptor subtype 5 (SSTR5) antagonist with IC50s of 9.6 and 57 nM for hSSTR5 and mSSTR5, respectively. (Compound 25a)

For research use only. We do not sell to patients.

SSTR5 antagonist 1 Chemical Structure

SSTR5 antagonist 1 Chemical Structure

CAS No. : 1628741-91-2

Size Price Stock Quantity
10 mM * 1 mL in DMSO USD 394 In-stock
Estimated Time of Arrival: December 31
5 mg USD 350 In-stock
Estimated Time of Arrival: December 31
10 mg USD 550 In-stock
Estimated Time of Arrival: December 31
25 mg USD 990 In-stock
Estimated Time of Arrival: December 31
50 mg USD 1650 In-stock
Estimated Time of Arrival: December 31
100 mg USD 2250 In-stock
Estimated Time of Arrival: December 31
200 mg   Get quote  
500 mg   Get quote  

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Based on 1 publication(s) in Google Scholar

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Description

SSTR5 antagonist 1 is a potent, selective, and orally available somatostatin receptor subtype 5 (SSTR5) antagonist with IC50s of 9.6 and 57 nM for hSSTR5 and mSSTR5, respectively. (Compound 25a)[1]

IC50 & Target

IC50: 9.6 nM (hSSTR5), 57 nM (mSSTR5)[1]

Molecular Weight

511.59

Formula

C₂₈H₃₄FN₃O₅

CAS No.

1628741-91-2

SMILES

OC(C1CCN(C2=NOC3(CN(CC4=CC(OCC)=C(C5=CC=C(F)C=C5)C(OCC)=C4)C3)C2)CC1)=O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage
Powder -20°C 3 years
  4°C 2 years
In solvent -80°C 6 months
  -20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 90 mg/mL (175.92 mM; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.9547 mL 9.7735 mL 19.5469 mL
5 mM 0.3909 mL 1.9547 mL 3.9094 mL
10 mM 0.1955 mL 0.9773 mL 1.9547 mL
*Please refer to the solubility information to select the appropriate solvent.
In Vivo:
  • 1.

    Add each solvent one by one:  10% DMSO    40% PEG300    5% Tween-80    45% saline

    Solubility: ≥ 2.25 mg/mL (4.40 mM); Clear solution

  • 2.

    Add each solvent one by one:  10% DMSO    90% (20% SBE-β-CD in saline)

    Solubility: ≥ 2.25 mg/mL (4.40 mM); Clear solution

  • 3.

    Add each solvent one by one:  10% DMSO    90% corn oil

    Solubility: ≥ 2.25 mg/mL (4.40 mM); Clear solution

*All of the co-solvents are provided by MCE.
References
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  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

Keywords:

SSTR5 antagonist 1Somatostatin ReceptorSSTRsSSTRInhibitorinhibitorinhibit

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Product name:
SSTR5 antagonist 1
Cat. No.:
HY-102037
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