Liposome
Liposomes (NPs typically 100–500 nm in diameter) are fabricated from the self-assembly of phospholipids, which consist of a polar phosphate head group and hydrophobic lipid tails. In aqueous environments, the hydrophobic tails self-orient, resulting in a spherical structure comprised of an aqueous core surrounded by a lipophilic bilayer membrane. Liposomes are both biocompatible and biodegradable (e.g., at certain pH and temperature), which can be controlled by modifying the lipid composition. Furthermore, liposomes are amenable to various modifications that improve their efficacy as drug delivery carriers.
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Liposome Related Products (1030)
Related Products (1030)
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DSPE-PEG3400-WLSEAGPVVTVRALRGTGSW
0 ImagesCat. No.: HY-177204BDSPE-PEG3400-WLSEAGPVVTVRALRGTGSW is a PEG compound which composed of DSPE and a cardiomyocyte specific peptide (WLSEAGPVVTVRALRGTGSW) (HY-P3436). WLSEAGPVVTVRALRGTGSW exhibits high cardiomyocyte targeting primarily through selective binding to specific receptors or molecules on the surface of cardiomyocytes. DSPE-PEG3400-WLSEAGPVVTVRALRGTGSW can be used for drug delivery.
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1,2-Didecanoyl-sn-glycero-3-phosphoethanolamine
0 ImagesCat. No.: HY-W140488CAS No.: 253685-27-7Synonyms: 10:0 PE1,2-Didecanoyl-sn-glycero-3-phosphoethanolamine, a phospholipid, showes very promising P-gp inhibitory results at a concentration of 0.3 mM.
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1,2-Dioleoyl-sn-glycero-3-phospho-(1'-myo-inositol-5'-phosphate) ammonium
0 ImagesCat. No.: HY-157699CAS No.: 1246303-10-51,2-Dioleoyl-sn-glycero-3-phospho-(1'-myo-inositol-5'-phosphate) ammonium is a membrane-bound signaling molecule with intracellular activity in regulating membrane trafficking and signal transduction. 1,2-Dioleoyl-sn-glycero-3-phospho-(1'-myo-inositol-5'-phosphate) ammonium can be used in the preparation of liposomes to enhance the efficiency of compound delivery. 1,2-Dioleoyl-sn-glycero-3-phospho-(1'-myo-inositol-5'-phosphate) ammonium can also act as a coordinator of the actin cytoskeleton and participate in the regulation of cell morphology and motility.
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EC1454
0 ImagesCat. No.: HY-128937CAS No.: 1602487-15-9EC1454 is a peptide compound with anticancer activity that targets folate receptor-expressing cancers. EC1454 is a folate-tubulysin conjugate that can be used to prepare drug delivery conjugates for targeted therapy.
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Phospholipid-PEG3400-Biotin
0 ImagesCat. No.: HY-147207BPhospholipid-PEG3400-Biotin is a phospholipid PEG derivative that has a biotin and a phospholipid bridged by a linear PEG linker. Phospholipid-PEG3400-Biotin can interact with avidinylated antibodies. Phospholipid-PEG3400-Biotin can be used to modify liposome and cells surface, and pancreatic islets for cell transplantation.
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DSPE-PEG3400-Mal-Cys-DT7
0 ImagesCat. No.: HY-179677ADSPE-PEG3400-Mal-Cys-DT7 is a phospholipid-PEG conjugate. DSPE-PEG3400-Mal-Cys-DT7 utilizes the amphiphilicity of DSPE to insert into the lipid bilayer of liposomes or nanoparticles.
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DSPE-PEG1000-TH
0 ImagesCat. No.: HY-172692DSPE-PEG1000-TH is a PEG compound which composed of DSPE and a pH-responsive cell penetrating peptide (TH). TH is activated in an acidic environment (such as the tumor microenvironment) and can selectively carry small molecules, oligonucleotides, proteins, etc. into tumor cells.
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OH-Chol
0 ImagesCat. No.: HY-145523CAS No.: 191173-82-7OH-Chol is a cationic cholesterol derivative. OH-Chol can be used for siRNA delivery and gene silencing.
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DSPE-PEG2000-DHLASLWWGTEL
0 ImagesCat. No.: HY-182099ADSPE-PEG2000-DHLASLWWGTEL is a PEG compound which composed of DSPE and a GPC3 targeting peptide DHLASLWWGTEL. The DHLASLWWGTEL peptide partially and specifically binds to GPC3-positive cells, achieving precise targeting. DSPE-PEG2000-DHLASLWWGTEL can be used for drug delivery.
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2N12B
0 ImagesCat. No.: HY-172334CAS No.: 3067164-96-62N12B is a bioreducible ionizable lipid containing disulfide bonds. 2N12B can be used to prepare lipid nanoparticles (LNPs) for the delivery of mRNA in vitro and in vivo. Lipid nanoparticles containing 2N12B can deliver siRNA to inhibit retinal neovascularization.
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DSPE-PEG3400-octreotide
0 ImagesCat. No.: HY-172280CDSPE-PEG3400-Octreotide is a PEG compound which composed of DSPE and a Octreotide (HY-P0036). Octreotide is a somatostatin receptor agonist. Octreotide has antitumor activity, mediates apoptosis and may also be used in disease studies in acromegaly. DSPE-PEG3400-Octreotide can be used for drug delivery.
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DSPE-PEG5000-CCK8
0 ImagesCat. No.: HY-172281BDSPE-PEG5000-CCK8 is a PEG compound which composed of DSPE and a Cholecystokinin-8 (CCK8). Cholecystokinin-8 has the activity of peptide regulating gallbladder contraction and digestive system function. DSPE-PEG5000-CCK8 can be used for drug delivery.
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DSPE-Pyrene
0 ImagesCat. No.: HY-W441021CAS No.: 2933318-11-5DSPE-Pyrene is a phospholipid molecule with polycyclic aromatic hydrocarbon, and can be used for drug encapsulation, such as drug loaded liposomes or nanoparticles. Pyrene is a fluorescent probe whose spectrum is sensitive to the polarity of its environment.
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Lipid C2
0 ImagesCat. No.: HY-169480CAS No.: 3003022-09-8Lipid C2 is an ionizable cationic lipid that has been used in the formation of lipid nanoparticles (LNP) for mRNA delivery in vivo. LNPs containing Lipid C2 and encapsulating an mRNA reporter selectively accumulate in the liver and spleen but not the heart, lungs, or kidneys in mice. LNP containing Lipid C2 and encapsulating mRNA encoding the Epstein-Barr virus (EBV) protein latent membrane protein 2 (LMP-2), in combination with an anti-programmed cell death protein 1 (PD-1) antibody, decrease tumor volume and reverse T cell exhaustion, as well as increase the percentage of CD3+CD8+ central and CD3+CD8+ effector memory T cells and decrease the percentage of CD3+ T cells expressing Pd-1, in the spleen in a CT26 murine EBV-infected colon cancer model.
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Oleyl Mesylate
0 ImagesCat. No.: HY-142985CAS No.: 35709-09-2Oleyl Mesylate is a derivative of Oleyl Alcohol. Oleyl Alcohol has been incorporated into various formulations for drug delivery.
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PPPDA-O16B
0 ImagesCat. No.: HY-159711CAS No.: 3097638-12-2PPPDA-O16B is a lipid containing disulfide bonds used for DNA delivery. PPPDA-O16B can encapsulate DNA plasmid, releasing DNA selectively via lipid degradation catalyzed by GSH.
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DSPE-PEG3400-R8
0 ImagesCat. No.: HY-172276CDSPE-PEG3400-R8 is a PEG compound which composed of DSPE and a cell-penetrating peptide (R8). pDSPE-PEG3400-R8 can be used for drug delivery.
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DSPE-PEG2000-Mal-Cys-ATWLPPR
0 ImagesCat. No.: HY-172272ADSPE-PEG2000-A7R is a PEG compound which composed of DSPE and a tumor vascular targeting peptide (A7R). A7R exhibits high affinity and specificity for VEGFR-2, which is overexpressed in various tumors.
