Liposome
Liposomes (NPs typically 100–500 nm in diameter) are fabricated from the self-assembly of phospholipids, which consist of a polar phosphate head group and hydrophobic lipid tails. In aqueous environments, the hydrophobic tails self-orient, resulting in a spherical structure comprised of an aqueous core surrounded by a lipophilic bilayer membrane. Liposomes are both biocompatible and biodegradable (e.g., at certain pH and temperature), which can be controlled by modifying the lipid composition. Furthermore, liposomes are amenable to various modifications that improve their efficacy as drug delivery carriers.
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Liposome Related Products (1030)
Related Products (1030)
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PtdIns-(3)-P1(1,2-dioctanoyl) sodium
0 ImagesCat. No.: HY-131482CAS No.: 299216-98-1PtdIns-(3)-P1(1,2-dioctanoyl) sodium (compound 1b) is a glycogen phosphate that plays a key role in eukaryotic membrane trafficking and agonist-activated intracellular signaling.
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DSPC-d13
0 ImagesSynonyms: 1,2-Distearoyl-sn-glycero-3-PC-d13; 1,2-Distearoyl-sn-glycero-3-phosphorylcholine-d13DSPC-d13 (1,2-Distearoyl-sn-glycero-3-phosphorylcholine-d13) is the deuterium labeled DSPC (HY-W040193). DSPC is a cylindrical-shaped lipid. 1,2-Distearoyl-sn-glycero-3-phosphorylcholine is used to synthesize liposomes, and is the lipid component in the lipid nanoparticle (LNP) system.
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DSPE-PEG5000-LTLRWVGLMS
0 ImagesCat. No.: HY-172486DSPE-PEG5000-LTLRWVGLMS is a PEG compound which composed of DSPE and a decapeptide (LTLRWVGLMS). The chondroitin sulfate proteoglygan NG2 is a receptor for LTLRWVGLMS. LLRWVGLMS shows the homing of pericytes associated with tumor blood vessels. DSPE-PEG5000-LTLRWVGLMS can be used for drug delivery.
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DSPC-d79
0 ImagesSynonyms: 1,2-Distearoyl-sn-glycero-3-PC-d79; 1,2-Distearoyl-sn-glycero-3-phosphorylcholine-d79DSPC-d79 (1,2-Distearoyl-sn-glycero-3-phosphorylcholine-d79) is the deuterium labeled DSPC (HY-W040193). DSPC is a cylindrical-shaped lipid. 1,2-Distearoyl-sn-glycero-3-phosphorylcholine is used to synthesize liposomes, and is the lipid component in the lipid nanoparticle (LNP) system.
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DSPE-PEG3400-GRGDS
0 ImagesCat. No.: HY-172684ADSPE-PEG3400-GRGDS is a PEG compound which composed of DSPE and an anti-adhesion peptide (GRGDS). GRGDS can block the binding and adhesion of extracellular matrix to cell surface integrins. DSPE-PEG3400-GRGDS can be used for drug delivery.
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Lipid I97
0 ImagesCat. No.: HY-171898CAS No.: 3046404-81-0Lipid I97 is an ionizable lipid derived from vitamin B5 (pKa = 6.23). Lipid I97 can be used to generate lipid nanoparticles (LNPs) for mRNA delivery in vivo. Lipid I97 can be studied in research for enhancing mRNA transfection efficiency and long-term stability as well as formulation of mRNA vaccines.
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1,2-Dioctanoyl-sn-glycero-3-phosphocholine
0 Images1,2-dioctanoyl-sn-glycero-3-phosphocholine, is a phospholipid commonly used as a component of liposome formulations and drug delivery systems. 1,2-dioctanoyl-sn-glycero-3-phosphocholine has unique chemical properties that allow it to form stable bilayers and vesicles, allowing drug encapsulation and delivery to specific targets in the body. It acts as a stabilizer and emulsifier, which can improve the solubility and bioavailability of drugs.
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C12 DG PEG (MW 2000)
0 ImagesCat. No.: HY-173376Synonyms: 1,2-Didodecanoyl-rac-glycero-3-methoxypolyethylene glycol (MW 2000)C12 DG PEG (1,2-Didodecanoyl-rac-glycero-3-methoxypolyethylene glycol) (MW 2000) is a PEG lipid that can be used in lipid nanoparticle and liposome formation. C12 DG PEG (MW 2000) is promising for research of cancers.
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DSPE-PEG3400-EB1
0 ImagesCat. No.: HY-172726ADSPE-PEG3400-EB1 is a PEG compound which composed of DSPE and pH responsive membrane-penetrating peptide (EB1). DSPE-PEG3400-EB1 can be used for drug delivery.
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PBA-Q76-O16B
0 ImagesCat. No.: HY-185778CAS No.: 3027931-27-4PBA-Q76-O16B is a lipid that cannot cross the blood-brain barrier on its own, but can mediate cargo delivery into the brains of mice when blended with NT1 lipids. After forming stable small-sized lipid nanoparticles with NT1-O12B, PBA-Q76-O16B delivers drugs into the brains of mice. When formulated into lipid nanoparticles with NT1-O14B, PBA-Q76-O16B delivers (-27) GFP-Cre recombinase into mouse brain cells, driving functional gene recombination in multiple brain regions. PBA-Q76-O16B can be used in studies related to lipid nanoparticles (LNPs).
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16:0 Cyanur PE
0 ImagesCat. No.: HY-W800798CAS No.: 1246304-37-9Synonyms: 1,2-dipalmitoyl-sn-glycero-3-phosphoethanolamine-N-(cyanur)16:0 Cyanur PE is a cyanur-functionalized lipid attached to a phosphoethanolamine linked to two palmitic acid groups.
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DSPE-PEG5000-SPDP
0 ImagesCat. No.: HY-W440901DSPE-PEG5000-SPDP is an amphiphilic polyPEG which forms lipid bilayer in water. It can be used to encapsualte therapeutic agents. The core can encapsulate hydrophilic nutrients, such as protein/peptide and mRNA/DNA/siRNA etc. while the lipid bilayer can solubilize hydrophobic drugs, such as doxorubicin, curcumin etc. The SPDP moiety can react with thiol molecule to form a disulfide bond.
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DPPE-PEG1000
0 ImagesCat. No.: HY-144012DCAS No.: 474922-84-4Synonyms: 16:0 PEG1000 PE; 1,2-Dipalmitoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy(polyethylene glycol)-1000] ammoniumDPPE-PEG1000 is a PEG lipid functional end group used in the synthesis of liposomes (LPs) for the design of conjugated polymer nanoparticles. Through biotin modification and carboxyl terminus, lipid nanoparticles (LNPs) further coupling with other biomolecules can be achieved. Functionalized nanoparticles can be used for targeted labeling of specific cellular proteins. With streptavidin as a linker, biotinylated PEG lipid-conjugated polymer nanoparticles are able to bind to biotinylated antibodies on cell surface receptors, yielding the utility of fluorescence-based imaging and sensing.
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Cholesterol-PEG3400-Thiol
0 ImagesCat. No.: HY-W440724Cholesterol-PEG3400-Thiol is an amphiphatic PEG derivative which forms micelles in water and can be used to prepare liposomes or nanoparticles for drug delivery system. The thiol moiety is reactive with maleimide to form a stable thioether bond.
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Lipopeptide CPE4
0 ImagesCat. No.: HY-P11455Lipopeptide CPE4 is a PEG-modified peptide E4 [(EIAALEK)4]. Lipopeptide CPE4 is capable of coiled-coil formation when attached to liposomes. Lipopeptide CPE4 triggers membrane fusion between liposomes and living cells with concomitant efficient cytosolic delivery of a variety of compounds such as fluorescent dyes Propidium Iodide (PI) (HY-D0815) and TO-PRO-3 iodide (HY-117070), and Doxorubicin (DOX) (HY-15142A). Lipopeptide CPE4 can be used for drug delivery research.
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Lipopeptide CPK4
0 ImagesCat. No.: HY-P11456Lipopeptide CPK4 is a Cholesterol (HY-N0322)-modified peptide K4 [(KIAALKE)3]. Lipopeptide CPK4 is capable of coiled-coil formation when attached to liposomes. Lipopeptide CPK4 triggers membrane fusion between liposomes and living cells with concomitant efficient cytosolic delivery of a variety of compounds such as fluorescent dyes Propidium Iodide (PI) (HY-D0815) and TO-PRO-3 iodide (HY-117070), and Doxorubicin (DOX) (HY-15142A). Lipopeptide CPK4 can be used for drug delivery research.
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DSPE-PEG3400-NYZL1
0 ImagesCat. No.: HY-172702ADSPE-PEG3400-NYZL1 is a PEG compound which composed of DSPE and a NYZL1 peptide. NYZL1 can specifically bind to bladder cancer tissues and cells. DSPE-PEG3400-NYZL1 can be used for drug delivery.
