DSPE-PEG3000-Mal-Cys-CGNKRTRGC (Disulfide bridge: Cys2-Cys10)
DSPE-PEG3000-LyP-1 is a PEG compound which composed of DSPE and a nine residue peptide (LyP-1) (HY-P2526). LyP-1 is a cyclic 9-amino-acids tumor homing peptide and selectively bind to p32 receptors overexpressed in various tumor-associated cells.
Para uso exclusivo en investigación. No vendemos a pacientes.
- Peso molecular:3000 (Average)
-
Almacenamiento:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
-
Actividad biológica
-
Chemical Information
- Pureza y Documentación
- Referencias
-
Help & FAQs
Actividad biológica
DSPE (distearate phosphatidylethanolamine): Acts as a hydrophobic anchor. Its two long hydrophobic chains are stably embedded in the lipid bilayer of the nanocarrier.
PEG3000 (polyethylene glycol, molecular weight 3000 Da): Acts as a hydrophilic linker and cryptic layer. Provides long-cycle functionality and exposes active peptides on the nanoparticle surface.
CGNKRTRGC (Lyp-1): A cyclic nonapeptide formed by disulfide bonds between two cysteine residues at the N- and C-termini. CGNKRTRGC specifically recognizes and binds to neurociliaryin-1, which is highly expressed on the surface of tumor lymphatic endothelial cells and certain tumor cells.
DSPE-PEG3000-Mal-Cys-CGNKRTRGC (Disulfide bridge: Cys2-Cys10) enables active targeting and penetration of tumor tissue.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
-
Peso molecular 3000 (Average)
-
SMILES
[Mal-Cys-CGNKRTRGC (Disulfide bridge: Cys2-Cys10)]C(CCOCCOC(NCCOP(OC[C@](COC(CCCCCCCCCCCCCCCCC)=O)([H])OC(CCCCCCCCCCCCCCCCC)=O)(O)=O)=O)=O.[n]
-
Envío
Room temperature in continental US; may vary elsewhere.
-
Almacenamiento
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureza y Documentación
Referencias
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
DSPE-PEG3000-Mal-Cys-CGNKRTRGC (Disulfide bridge: Cys2-Cys10) Related Classifications
HY-172271B Related Classifications
Powered by Bioz