Drug Intermediate
Drug Iintermediate
Drug intermediates are used as raw materials for the production of bulk drugs, or they can refer to a material produced during synthesis of an API that must undergo further molecular change or processing before it becomes an API. Drug intermediates are hygienically formulated using high grade raw materials and they are used in the pharmaceutical and cosmetic industry[1][2].
References:
- [1]. Ma HC, et al. Homochiral Covalent Organic Framework for Catalytic Asymmetric Synthesis of a Drug Intermediate. J Am Chem Soc. 2020 Jul 22;142(29):12574-12578. [Content Brief]
- [2]. Ramachary D B, et al. Development of pharmaceutical drugs, drug intermediates and ingredients by using direct organo‐click reactions[J]. 2008.
All Product Categories
-
Drug Intermediate Related Products (4595)
Related Products (4595)
-
2-Hydroxypalmitic acid
0 Images2-Hydroxypalmitic acid is an intermediate in the phytosphingosine metabolic pathway. 2-Hydroxypalmitic acid is exclusively incorporated into sphingolipids and not used for other lipids. 2-Hydroxypalmitic acid promotes the production of odd-carbon phosphatidylcholine species. 2-Hydroxypalmitic acid is applicable to studies of Saccharomyces cerevisiae infection.
-
Azetidine hydrochloride
0 ImagesCat. No.: HY-W010628CAS No.: 36520-39-5Synonyms: Trimethyleneimine hydrochlorideAzetidine (Trimethyleneimine) hydrochloride is a biochemical reagent that can be used as a biological material or organic compound for life science related research. Azetidine hydrochloride is also a nitrogen-containing heterocyclic compound, which can be used in the synthesis of other active compounds.
-
(S)-(-)-1-Phenylethanamine
0 ImagesSynonyms: S-(-)-α-Phenylethylamine; L-(-)-α-Methylbenzylamine(S)-(-)-1-Phenylethanamine (S-(-)-α-Phenylethylamine; L-(-)-α-Methylbenzylamine) is a S-isomer of 1-Phenylethanamine (HY-W012848). (S)-(-)-1-Phenylethanamine can be used as a pharmaceutical intermediate for the synthesis of various active compounds.
-
1-Boc-3-iodoazetidine
0 Images1-Boc-3-iodoazetidine acts as a bifunctional additive for lithium-oxygen (Li-O2) batteries and can be used to enhance the performance of Li-O2 batteries. 1-Boc-3-iodoazetidine is applied in the synthesis of C3-functionalized azetidines and C2-functionalized azetidines via a lithium/iodine exchange or β-elimination/lithiation reaction sequence.
-
Indole-3-methanamine
0 ImagesIndole-3-methanamine is an indole derivative, stress-related metabolite, and also a biosynthetic precursor of Gramine (HY-N0166). The accumulation level of Indole-3-methanamine increases in susceptible barley varieties infected with Bipolaris sorokiniana. Indole-3-methanamine can be used in studies related to barley spot blotch.
-
1-Cyclopropyl-4-ethynyl-1H-pyrazole
0 Images1-Cyclopropyl-4-ethynyl-1H-pyrazole is a drug intermediate for synthesis of various active compounds.
-
4-Methoxybenzyl alcohol
0 ImagesSynonyms: P-Methoxy-benzyl alcoho; (4-Methoxyphenyl)methanol4-Methoxybenzyl alcohol (P-Methoxy-benzyl alcoho; (4-Methoxyphenyl) methanol) is a naturally derived volatile aromatic compound. 4-Methoxybenzyl alcohol upregulates the phosphorylation level of PI3K/Akt pathway proteins, downregulates the expression of pro-inflammatory factors, increases the content of tight junction proteins occludin and claudin-5, and alleviates structural damage to the blood-brain barrier. 4-Methoxybenzyl alcohol improves the decrease in viability and NO level of cerebral microvascular endothelial cells induced by oxygen-glucose deprivation/reperfusion, and reduces the release of lactate dehydrogenase. 4-Methoxybenzyl alcohol serves as a substrate in the two-phase persulfate-mediated electro-oxidation system, where it is directionally oxidized to p-anisaldehyde. 4-Methoxybenzyl alcohol acts as a substrate for wild-type fungal aryl alcohol oxidase. 4-Methoxybenzyl alcohol can be used in studies related to ischemic stroke, as well as in research across various fields such as chemical synthesis, including the synthesis of fragrances and flavorings.
-
2-(4-Fluorobenzylamino)ethanol
0 Images2-(4-Fluorobenzylamino)ethanol is a drug intermediate for synthesis of various active compounds.
-
Ethyl 5-(piperazin-1-yl)benzofuran-2-carboxylate hydrochloride
0 ImagesEthyl 5-(piperazin-1-yl)benzofuran-2-carboxylate hydrochloride is a drug intermediate for synthesis of various active compounds.
-
6-Heptynoic acid
0 ImagesSynonyms: Hept-6-ynoic acidHexanoylic acid (Hex-6-ynoic acid) is a drug intermediate. Hexanoylic acid can be functionalized by esterification reaction to paclitaxel (HY-B0015), enabling it to undergo an efficient ring addition reaction with β-cyclodextrin, thereby enhancing its water solubility, stability and targeting properties.
-
6-Bromo-4-chloroquinoline
0 Images6-Bromo-4-chloroquinoline is a drug intermediate for synthesis of various active compounds.
-
3-Methoxy-4-(4-methyl-1H-imidazol-1-yl)benzaldehyde
0 Images3-Methoxy-4-(4-methyl-1H-imidazol-1-yl)benzaldehyde is a drug intermediate for synthesis of various active compounds.
-
3-Methyl-6-nitro-1H-indazole
0 Images3-Methyl-6-nitro-1H-indazole is a drug intermediate for synthesis of various active compounds.
-
(3S)-Fmoc-1-pyrrolidine-3-carboxylic acid
0 Images(3S)-Fmoc-1-pyrrolidine-3-carboxylic acid is a drug intermediate for synthesis of various active compounds.
-
2-Fluoro-5-formylbenzoic acid
0 Images2-Fluoro-5-formylbenzoic acid is a drug intermediate for synthesis of various active compounds.
-
2,3-Dimethyl-6-nitro-2H-indazole
0 ImagesSynonyms: Pazopanib Impurity2,3-Dimethyl-6-nitro-2H-indazole (Pazopanib Impurity) is a drug intermediate for synthesis of various active compounds.
-
Salicyl alcohol
0 ImagesSalicyl alcohol (2-Hydroxybenzyl alcohol; Saligenin) is a phenolic alcohol-type topical anesthetic and strong sensitizer with antiseptic, antibacterial and antipyretic activities. Salicyl alcohol serves as a precursor for salicin synthesis. Salicyl alcohol induces contact dermatitis and eczematous skin reactions, and is a well-known allergen identified in phenolic resins. Salicyl alcohol is isolated from the barks of European aspen (Populus tremula), rowan (Sorbus aucuparia) and willow (Salix spp.). Salicyl alcohol is used in studies related to allergic contact dermatitis.
-
(3,4-Dimethoxyphenyl)hydrazine hydrochloride
0 Images(3,4-Dimethoxyphenyl)hydrazine hydrochloride is a drug intermediate for synthesis of various active compounds.
