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  4. Drug Intermediate

Drug Intermediate

Drug Iintermediate

Drug intermediates are used as raw materials for the production of bulk drugs, or they can refer to a material produced during synthesis of an API that must undergo further molecular change or processing before it becomes an API. Drug intermediates are hygienically formulated using high grade raw materials and they are used in the pharmaceutical and cosmetic industry[1][2].

Drug Intermediate Related Products (4346):

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-43384
    Chloromethyl methyl carbonate
    		99.28%
    Chloromethyl methyl carbonate (Tenofovir Impurity 66) is a drug intermediate for synthesis of various active compounds.
    Chloromethyl methyl carbonate
  • HY-20456
    4-Chloro-6,7-dimethoxyquinoline
    		99.91%
    4-Chloro-6,7-dimethoxyquinoline (Oro-6,7-dimethoxyquinol) is a drug intermediate for synthesis of various active compounds.
    4-Chloro-6,7-dimethoxyquinoline
  • HY-W016287
    Adamantane-1,3,5-triol
    Adamantane-1,3,5-triol is a drug intermediate for synthesis of various active compounds.
    Adamantane-1,3,5-triol
  • HY-76667
    3-(Boc-amino)propyl bromide
    		99.95%
    3-(Boc-amino) propyl bromide is an alkylating reagent used for the N-alkylation of benzopyranotriazolopyrimidine-based MDM2-p53 protein-protein inhibitor 4 to prepare Compound 13.
    3-(Boc-amino)propyl bromide
  • HY-W092039
    3-(But-3-yn-1-yl)-3-(2-iodoethyl)-3H-diazirine
    		98.0%
    3-(But-3-yn-1-yl)-3-(2-iodoethyl)-3H-diazirine is a drug intermediate for synthesis of various active compounds.
    3-(But-3-yn-1-yl)-3-(2-iodoethyl)-3H-diazirine
  • HY-59157
    7-Methyl-1,5,7-triazabicyclo[4.4.0]dec-5-ene
    		99.19%
    7-Methyl-1,5,7-triazabicyclo[4.4.0]dec-5-ene is a drug intermediate for synthesis of various active compounds.
    7-Methyl-1,5,7-triazabicyclo[4.4.0]dec-5-ene
  • HY-59219
    Cyclopropylboronic acid
    		99.22%
    Cyclopropylboronic acid is an intermediate. Cyclopropylboronic acid can be used to synthesize EGFR kinase inhibitor (Compound 25). Compound 25 has antiproliferative effects on EGFR mutant (EGFR Δ19del/T790M/C797S) cells. Cyclopropylboronic acid can be used in lung cancer research.
    Cyclopropylboronic acid
  • HY-W590989
    GPhos Pd G6
    		98.50%
    GPhos Pd G6 (GPhos Pd G6 TES) is a palladium catalyst. GPhos Pd G6 catalyzes the Buchwald-Hartwig amination reaction and promotes C-N bond formation between aryl chlorides and amines. GPhos Pd G6 is a pharmaceutical intermediate used for the synthesis of various active compounds.
    GPhos Pd G6
  • HY-21206
    1-(((4-Nitrophenoxy)carbonyl)oxy)ethyl isobutyrate
    		99.92%
    1-(((4-Nitrophenoxy)carbonyl)oxy)ethyl isobutyrate is a drug intermediate for synthesis of various active compounds.
    1-(((4-Nitrophenoxy)carbonyl)oxy)ethyl isobutyrate
  • HY-45545
    Fmoc-Gly-Gly-Phe-Gly-NH-CH2-O-CH2COOH
    		99.95%
    Fmoc-gly-gly-ph-gly-nh-ch2-o-ch2cooh can be used to synthesize the ADC Linker, LND1067.
    Fmoc-Gly-Gly-Phe-Gly-NH-CH2-O-CH2COOH
  • HY-W127512
    5β-Cholanic acid
    		99.87%
    5β-Cholanic acid is a hydrophobic modifier used to modify polymer carriers. 5β-Cholanic acid can improve the acid stability, cell penetration efficiency and drug sustained release ability of nanocarriers, and optimize the oral effectiveness of delivered molecules. 5β-Cholanic acid can covalently bind to Glycol chitosan (GC) to form a GC-CA conjugate, which optimizes the hydrophobic anchoring ability of nanoparticles and enables them to be stably adsorbed on the surface of PLGA nanoparticles. Such nanoparticles can resist dissociation in the gastric acid environment and maintain positive charge to enhance endocytic uptake by intestinal epithelial cells (such as Caco-2 cells). 5β-Cholanic acid can be used in the development of drug delivery systems.
    5β-Cholanic acid
  • HY-142104
    2-CTC Resin (100-200 mesh,1% DVB,0.4-3.0mmol/g)
    2-CTC Resin (100-200 mesh,1% DVB,0.4-3.0mmol/g) is a solid-phase synthesis carrier that has been used to study metabolic disorders in prostate cancer cells. 2-CTC Resin (100-200 mesh,1% DVB,0.4-3.0mmol/g) can be used as a reaction solution of terminal residues and adenine nucleotides to form cyclic peptides. 2-CTC Resin (100-200 mesh,1% DVB,0.4-3.0mmol/g) can prevent racemization during the incorporation of the first protected amino acid and minimized diketopiperazine formation. 2-CTC Resin (100-200 mesh,1% DVB,0.4-3.0mmol/g) is one of the most commonly used and versatile resins available for large-scale production of peptides.
    2-CTC Resin (100-200 mesh,1% DVB,0.4-3.0mmol/g)
  • HY-143221
    AS-Inclisiran sodium
    AS-Inclisiran sodium is the antisense of Inclisiran (HY-132591). Inclisiran is a double-stranded small interfering RNA (siRNA) molecule. Inclisiran inhibits the transcription of PCSK9. Inclisiran inhibits Pyroptosis, activates PPARγ, and reduces NLRP3, cleaved caspase-1, IL-1β, and IL-18. Inclisiran has anti-inflammatory, lipid-regulating and anti-atherosclerotic activities. Inclisiran can be used in researches of hyperlipidemia and cardiovascular disease (CVD).
    AS-Inclisiran sodium
  • HY-W002172
    2-Amino-5-chloro-2'-fluorobenzophenone
    		99.97%
    2-Amino-5-chloro-2'-fluorobenzophenone is a precursor in the synthesis of Midazolam.
    2-Amino-5-chloro-2'-fluorobenzophenone
  • HY-Y0335
    1,3-Dihydroxyacetone
    		99.49%
    1,3-Dihydroxyacetone (DHA), the main active ingredient in sunless tanning skin-care preparations and an important precursor for the synthesis of various fine chemicals, is produced on an industrial scale by microbial fermentation of glycerol (HY-B1659) in Gluconobacter oxydans. 1,3-Dihydroxyacetone is also used for synthesis of new biodegradable polymers by combining with lactic acid (HY-B2227).
    1,3-Dihydroxyacetone
  • HY-W061628
    (R)-Azetidin-2-ylmethanol
    		99.40%
    (R)-Azetidin-2-ylmethanol is a drug intermediate for synthesis of various active compounds.
    (R)-Azetidin-2-ylmethanol
  • HY-W017289
    4,4′-Dipyridyl
    		99.97%
    4,4′-Dipyridyl is a heterocyclic compound. 4,4′-Dipyridyl is utilized as an electronic and photosensitive building block and bidentate ligand in supramolecular chemistry. 4,4′-Dipyridyl can also be used as a drug intermediate in the synthesis of paraquat, a widely used herbicide.
    4,4′-Dipyridyl
  • HY-59333
    3-Methylazetidin-3-ol hydrochloride
    3-Methylazetidin-3-ol hydrochloride is a drug intermediate for synthesis of various active compounds.
    3-Methylazetidin-3-ol hydrochloride
  • HY-N3007
    Naringenin chalcone
    		98.86%
    Naringenin chalcone is an orally active intermediate in flavonol biosynthesis. Naringenin chalcone induces Apoptosis. Naringenin chalcone inhibits the production of MCP-1 and NO. Naringenin chalcone exhibits anticancer activity against glioblastoma. Naringenin chalcone has anti-inflammatory and anti-allergic properties.
    Naringenin chalcone
  • HY-W599085
    tert-Butyl (6-fluoro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-5-((triisopropylsilyl)ethynyl)naphthalen-2-yl)carbamate
    		99.79%
    tert-Butyl (6-fluoro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-5-((triisopropylsilyl)ethynyl)naphthalen-2-yl)carbamate is a drug intermediate that can be used for synthesis of various active compounds.
    tert-Butyl (6-fluoro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-5-((triisopropylsilyl)ethynyl)naphthalen-2-yl)carbamate