73692-50-9
73692-50-9
Chemical Structure
Naringenin chalcone
- CAS No.: 73692-50-9
- Formula:C15H12O5
- Molecular Weight:272.25
IUPAC Name: (E)-3-(4-hydroxyphenyl)-1-(2,4,6-trihydroxyphenyl)prop-2-en-1-one
InChIKey: YQHMWTPYORBCMF-ZZXKWVIFSA-N
SMILES: OC(C=C1)=CC=C1/C=C/C(C2=C(C=C(O)C=C2O)O)=O
Biological Activity: Naringenin chalcone is an orally active intermediate in flavonol biosynthesis. Naringenin chalcone induces Apoptosis. Naringenin chalcone inhibits the production of MCP-1 and NO. Naringenin chalcone exhibits anticancer activity against glioblastoma. Naringenin chalcone has anti-inflammatory and anti-allergic properties[1][2][3][4][5][6].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Naringenin chalcone | 98.86% | Naringenin chalcone is an orally active intermediate in flavonol biosynthesis. Naringenin chalcone induces Apoptosis. Naringenin chalcone inhibits the production of MCP-1 and NO. Naringenin chalcone exhibits anticancer activity against glioblastoma. Naringenin chalcone has anti-inflammatory and anti-allergic properties. | ||||||||||||||||||||
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Naringenin chalcone (Standard) | ≥98% | Naringenin chalcone (Standard) is an analytical standard of Naringenin chalcone. This product is intended for research and analytical applications. Naringenin chalcone is an orally active intermediate in the biosynthesis of flavonols. Naringenin chalcone induces apoptosis. Naringenin chalcone inhibits the production of MCP-1 and NO. Naringenin chalcone exhibits anticancer activity against glioblastoma. Naringenin chalcone has anti-inflammatory and anti-allergic properties. | ||||||||||||||||||||
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References
- [1]. Hirai S, et al. Inhibitory effect of naringenin chalcone on inflammatory changes in the interaction between adipocytes and macrophages. Life Sci. 2007 Sep 29;81(16):1272-9. [Content Brief]
- [2]. Iwamura C, et al. Naringenin chalcone suppresses allergic asthma by inhibiting the type-2 function of CD4 T cells. Allergol Int. 2010 Mar;59(1):67-73. [Content Brief]
- [3]. Zhang S, et al. Anti-cancer effect of naringenin chalcone is mediated via the induction of autophagy, apoptosis and activation of PI3K/Akt signalling pathway. Bangladesh Journal of Pharmacology, 2016, 11(3): 684-690.
- [4]. Horiba T, et al. Naringenin chalcone improves adipocyte functions by enhancing adiponectin production. Mol Cell Endocrinol. 2010 Jul 29;323(2):208-14. [Content Brief]
- [5]. Escribano-Ferrer E, et al. In Vivo Anti-inflammatory and Antiallergic Activity of Pure Naringenin, Naringenin Chalcone, and Quercetin in Mice. J Nat Prod. 2019 Feb 22;82(2):177-182. [Content Brief]
- [6]. Yoshimura M, et al. Identification and quantification of metabolites of orally administered naringenin chalcone in rats. J Agric Food Chem. 2009 Jul 22;57(14):6432-7. [Content Brief]
