870-46-2
Chemical Structure
tert-Butyl carbazate
- CAS No.: 870-46-2
- Formula:C5H12N2O2
- Molecular Weight:132.16
IUPAC Name: tert-butyl hydrazinecarboxylate
InChIKey: DKACXUFSLUYRFU-UHFFFAOYSA-N
SMILES: NNC(OC(C)(C)C)=O
Biological Activity:
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tert-Butyl carbazate | 98.93% | tert-Butyl carbazate serves as a starting material for the preparation of heterocyclic and hydrazine derivatives. tert-Butyl carbazate undergoes coupling with aryl, heteroaryl, and alkenyl boronic acids to synthesize doubly protected monosubstituted hydrazines. Derivatives of tert-Butyl carbazate exhibit varying degrees of inhibitory activity against Gram-positive bacteria, Gram-negative bacteria, and various fungi. |
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Similarity Score 0.82
HY-40171NH2-C2-NH-Boc -
Similarity Score 0.81
HY-34346tert-Butyl (2-hydrazinyl-2-oxoethyl)carbamate -
Similarity Score 0.80
HY-W007408tert-Butyl 2-aminoacetate -
Similarity Score 0.79
HY-75331Glycine tert-butyl ester hydrochloride -
Similarity Score 0.79
HY-40172tert-Butyl (3-aminopropyl)carbamate -
Similarity Score 0.79
HY-W007322Boc-NH-PEG1-OH -
Similarity Score 0.79
HY-1348532-(Boc-amino)ethanethiol -
Similarity Score 0.79
HY-W049677tert-Butyl (2-iodoethyl)carbamate -
Similarity Score 0.78
HY-W056118tert-Butyl N-[2-(aminooxy)ethyl]carbamate -
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References
- [1]. Kabalka GW, et al. Synthesis of diprotected monosubstituted hydrazine derivatives from tert-butyl carbazates and boronic acids. Org Lett. 2003;5(22):4129-4131. [Content Brief]
- [2]. Şahin G, et al. Synthesis and antimicrobial activity of some 1,3,4-oxadiazole derivatives. Il Farmaco. 2002 Jul;57(7):539-542.