Boc-NH-PEG1-OH
Based on 1 Customer Validation
Boc-NH-PEG1-OH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.
For research use only. We do not sell to patients.
- Purity: 99.65%
- CAS No.: 26690-80-2
- Formula: C7H15NO3
- Molecular Weight:161.20
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Storage:Pure form -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
All PROTAC Linkers Isoforms
More
Biological Activity
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PEGs |
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 26690-80-2
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Appearance Viscous Liquid
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Molecular Weight 161.20
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Formula C7H15NO3
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Color Colorless to light yellow
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SMILES
O=C(OC(C)(C)C)NCCO
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Pure form -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
DMSO : 100 mg/mL (620.35 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (268 KB)
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SDS (480 KB)
- English - EN (480 KB)
- Français - FR (480 KB)
- Deutsch - DE (480 KB)
- Norwegian - NO (480 KB)
- Español - ES (480 KB)
- Swedish - SV (480 KB)
- Italian - IT (480 KB)
- Korean - KR (480 KB)
- Portuguese - PT (480 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 6.2035 mL | 31.0174 mL | 62.0347 mL | 155.0869 mL |
| 5 mM | 1.2407 mL | 6.2035 mL | 12.4069 mL | 31.0174 mL | |
| 10 mM | 0.6203 mL | 3.1017 mL | 6.2035 mL | 15.5087 mL | |
| 15 mM | 0.4136 mL | 2.0678 mL | 4.1356 mL | 10.3391 mL | |
| 20 mM | 0.3102 mL | 1.5509 mL | 3.1017 mL | 7.7543 mL | |
| 25 mM | 0.2481 mL | 1.2407 mL | 2.4814 mL | 6.2035 mL | |
| 30 mM | 0.2068 mL | 1.0339 mL | 2.0678 mL | 5.1696 mL | |
| 40 mM | 0.1551 mL | 0.7754 mL | 1.5509 mL | 3.8772 mL | |
| 50 mM | 0.1241 mL | 0.6203 mL | 1.2407 mL | 3.1017 mL | |
| 60 mM | 0.1034 mL | 0.5170 mL | 1.0339 mL | 2.5848 mL | |
| 80 mM | 0.0775 mL | 0.3877 mL | 0.7754 mL | 1.9386 mL | |
| 100 mM | 0.0620 mL | 0.3102 mL | 0.6203 mL | 1.5509 mL |
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