96-26-4
Chemical Structure
1,3-Dihydroxyacetone
Synonym(s): Dihydroxyacetone
- CAS No.: 96-26-4
- Formula:C3H6O3
- Molecular Weight:90.08
IUPAC Name: 1,3-dihydroxypropan-2-one
InChIKey: RXKJFZQQPQGTFL-UHFFFAOYSA-N
SMILES: O=C(CO)CO
Biological Activity: 1,3-Dihydroxyacetone (DHA), the main active ingredient in sunless tanning skin-care preparations and an important precursor for the synthesis of various fine chemicals, is produced on an industrial scale by microbial fermentation of glycerol (HY-B1659) in Gluconobacter oxydans. 1,3-Dihydroxyacetone is also used for synthesis of new biodegradable polymers by combining with lactic acid (HY-B2227)[1][2].
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1,3-Dihydroxyacetone | 98.0% | 1,3-Dihydroxyacetone (DHA), the main active ingredient in sunless tanning skin-care preparations and an important precursor for the synthesis of various fine chemicals, is produced on an industrial scale by microbial fermentation of glycerol (HY-B1659) in Gluconobacter oxydans. 1,3-Dihydroxyacetone is also used for synthesis of new biodegradable polymers by combining with lactic acid (HY-B2227). | ||||||||||||||||||||
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1,3-Dihydroxyacetone (Standard) | 99.42% | 1,3-Dihydroxyacetone (Standard) is the analytical standard of 1,3-Dihydroxyacetone. This product is intended for research and analytical applications. 1,3-Dihydroxyacetone (DHA), the main active ingredient in sunless tanning skin-care preparations and an important precursor for the synthesis of various fine chemicals, is produced on an industrial scale by microbial fermentation of glycerol (HY-B1659) in Gluconobacter oxydans. 1,3-Dihydroxyacetone is also used for synthesis of new biodegradable polymers by combining with lactic acid (HY-B2227). | ||||||||||||||||||||
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Hydroxypyruvic acid | 98.0% | Hydroxypyruvic acid (β-Hydroxypyruvic acid) is an intermediate in the metabolism of glycine, serine and threonine. Hydroxypyruvic acid is a substrate for serine-pyruvate aminotransferase and glyoxylate reductase/hydroxypyruvate reductase. Hydroxypyruvic acid is involved in the metabolic disorder which is the dimethylglycine dehydrogenase deficiency pathway. | ||||||||||||||||||||
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1-Hydroxy-2-butanone (Standard) | ≥98% | 1-Hydroxy-2-butanone (Standard) is the analytical standard of 1-Hydroxy-2-butanone (HY-W005327). This product is intended for research and analytical applications. 1-Hydroxy-2-butanone is an intermediate. 1-Hydroxy-2-butanone can be used to synthesize Ethambutol (HY-B0535). Ethambutol exhibits anti-tuberculosis activity. | ||||||||||||||||||||
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Glycolic acid | 97.0% | Glycolic acid is an inhibitor of tyrosinase, suppressing melanin formation and lead to a lightening of skin colour. | ||||||||||||||||||||
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4-Hydroxy-2-butanone (Standard) | ≥98% | 4-Hydroxy-2-butanone (Standard) is the analytical standard of 4-Hydroxy-2-butanone (HY-W051287). This product is intended for research and analytical applications. 4-Hydroxy-2-butanone is a free volatile component of glycoside precursors in wax gourd. | ||||||||||||||||||||
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3-Hydroxypropionic acid (30% in water) | 3-Hydroxypropionic acid (30% in water) is a metabolite of β-Alanine (HY-N0230) and also a precursor for the synthesis of various chemical products. 3-Hydroxypropionic acid (30% in water) exhibits reduced urinary levels in elderly male patients with nocturia, which correlates with altered β-Alanine metabolic pathogenesis. 3-Hydroxypropionic acid (30% in water) can be used in studies related to nocturia. | |||||||||||||||||||||
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L-Erythrulose | 75.40% | L-Erythrulose is a class of biochemical reagents used in glycobiology research. Glycobiology studies the structure, synthesis, biology, and evolution of sugars. It involves carbohydrate chemistry, enzymology of glycan formation and degradation, protein-glycan recognition, and the role of glycans in biological systems. This field is closely related to basic research, biomedicine, and biotechnology. | ||||||||||||||||||||
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Glycolic acid-13C2 | Glycolic acid-13C2 is the 13C-labeled Glycolic acid (HY-W015967). Glycolic acid-13C2 is an inhibitor of tyrosinase, suppressing melanin formation and lead to a lightening of skin colour. | |||||||||||||||||||||
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Ethylene glycol,98% | 99.90% | Ethylene glycol is an organic compound that is often used as an antifreeze agent and coolant. Ethylene glycol lowers the freezing point by forming hydrogen bonds with water molecules, exerting antifreeze activity. Ethylene glycol is also used as a raw material in the synthesis of polymers such as polyester fibers and polyurethanes. | ||||||||||||||||||||
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Ethylene glycol-13C2 | 99.9% | Ethylene glycol-13C2 is the 13C labeled Ethylene glycol. | ||||||||||||||||||||
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Hydroxyacetone | 98.93% | Hydroxyacetone is a toxic compound. Hydroxyacetone can be isolated from e-cigarette aerosols. Hydroxyacetone reduces the activity of cellular Mitochondrial reductase (with an IC50 of 5.53 mg/mL for mitochondrial reductase in BEAS-2B cells) and increases ROS levels. Hydroxyacetone induces mitochondrial stress and oxidative damage. Hydroxyacetone induces destabilization of F-actin. At high concentrations, Hydroxyacetone promotes cell rounding and Apoptotic body formation. Hydroxyacetone exerts toxic effects on cells including airway epithelial cells and possesses respiratory toxicity potential.\n |
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References
- [1]. Zheng Z, et al. Novel Process for 1,3-Dihydroxyacetone Production from Glycerol. 1. Technological Feasibility Study and Process Design. Ind. Eng. Chem. Res. 2012, 51, 9, 3715–3721.
- [2]. Dikshit PK, et al. Optimization of 1,3-dihydroxyacetone production from crude glycerol by immobilized Gluconobacter oxydans MTCC 904. Bioresour Technol. 2016 Sep;216:1058-65. [Content Brief]