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Art. -Nr.: HY-160596

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5-Formyl-dCTP lithium

(Synonyms: 5-Formyl-deoxycytidine lithium)

5-Formyl-dCTP (5-Formyl-deoxycytidine) lithium is a DCTPP1 substrate. 5-Formyl-dCTP lithium acts as a mutagen/epigenetic disruptor via DNA polymerase incorporation, mutagenic mispairings, and disturbed epigenetic programming. 5-Formyl-dCTP lithium can be used for research on genotoxicity.

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CAS. Nr.: 2409156-19-8
Formel: C₁₀H₁₂Li₄N₃O₁₄P₃
Molecular Weight:518.90

Speicherung:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (270 KB)

5-Formyl-dCTP lithium Chemical Structure

CAS. Nr.: 2409156-19-8

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Biologische Aktivität
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Bioz

Biologische Aktivität

Beschreibung

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In Vitro

5-Formyl-dCTP lithium exhibits enriched, specific binding to Con A (K_d,eff = 20 nM) with minimal binding to PSA (K_d,eff > 1 μM) after three rounds of two-color click-PD screening^[1].
5-Formyl-dCTP lithium (10-250 μM) is hydrolysed by purified recombinant human DCTPP1 with high efficiency, exhibiting a K_m of 9.2 μM, the lowest substrate affinity reported for the enzyme, and a specificity constant of 322,000/M·s^[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS. Nr. 2409156-19-8
Molecular Weight 518.90
Formel C₁₀H₁₂Li₄N₃O₁₄P₃
SMILES

O=CC1=CN([C@@H](C[C@@H]2O)O[C@@H]2COP(OP(OP(O[Li])(O[Li])=O)(O[Li])=O)(O[Li])=O)C(N=C1N)=O
Synonyms

5-Formyl-deoxycytidine lithium
Versand

Room temperature in continental US; may vary elsewhere.
Speicherung

Please store the product under the recommended conditions in the Certificate of Analysis.

Reinheit & Dokumentation

Select Batch:

Reinheit: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (270 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

Verweise

[1]. Gordon CKL, et al. Click-Particle Display for Base-Modified Aptamer Discovery. ACS Chem Biol. 2019;14(12):2652-2662. [Content Brief]

[2]. Requena CE, et al. The NTP pyrophosphatase DCTPP1 contributes to the homoeostasis and cleansing of the dNTP pool in human cells. Biochem J. 2014;459(1):171-180. [Content Brief]

Calculators

Molaritätsrechner

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Konzentration Konzentration

Volumen Volumen

Molecular Weight Molecular Weight

Verdünnungsrechner

Konzentration _{(Stammlösung)} × Volumen _{(Stammlösung)} = Konzentration _{(Ziellösung)} × Volumen _{(Ziellösung)}

Konzentration _{(Stammlösung)} Konzentration _{(Stammlösung)}

Volumen _{(Stammlösung)} Volumen _{(Stammlösung)}

Konzentration _{(Ziellösung)} Konzentration _{(Ziellösung)}

Volumen _{(Ziellösung)} Volumen _{(Ziellösung)}

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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5-Formyl-dCTP lithium

Alle DNA/RNA Synthesis Isoform-spezifische Produkte anzeigen

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Chemical Information

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5-Formyl-dCTP lithium Related Classifications

HY-160596 Related Classifications