2409156-19-8
2409156-19-8
Chemical Structure
5-Formyl-dCTP lithium
Synonym(s): 5-Formyl-deoxycytidine lithium
- CAS No.: 2409156-19-8
- Formula:C10H12Li4N3O14P3
- Molecular Weight:518.90
InChIKey: MCHGSMXQXUSFEK-ZKRIHRHSSA-J
SMILES: O=CC1=CN([C@@H](C[C@@H]2O)O[C@@H]2COP(OP(OP(O[Li])(O[Li])=O)(O[Li])=O)(O[Li])=O)C(N=C1N)=O
Biological Activity: 5-Formyl-dCTP (5-Formyl-deoxycytidine) lithium is a DCTPP1 substrate. 5-Formyl-dCTP lithium acts as a mutagen/epigenetic disruptor via DNA polymerase incorporation, mutagenic mispairings, and disturbed epigenetic programming. 5-Formyl-dCTP lithium can be used for research on genotoxicity[1][2].
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5-Formyl-dCTP lithium | 5-Formyl-dCTP (5-Formyl-deoxycytidine) lithium is a DCTPP1 substrate. 5-Formyl-dCTP lithium acts as a mutagen/epigenetic disruptor via DNA polymerase incorporation, mutagenic mispairings, and disturbed epigenetic programming. 5-Formyl-dCTP lithium can be used for research on genotoxicity. | |||||||||||||||||||||
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References
- [1]. Gordon CKL, et al. Click-Particle Display for Base-Modified Aptamer Discovery. ACS Chem Biol. 2019;14(12):2652-2662. [Content Brief]
- [2]. Requena CE, et al. The NTP pyrophosphatase DCTPP1 contributes to the homoeostasis and cleansing of the dNTP pool in human cells. Biochem J. 2014;459(1):171-180. [Content Brief]
Keywords
