Arachidonic acid-d8
Based on 5 publication(s) in Google Scholar
Arachidonic acid-d8 is the deuterium labeled Arachidonic acid. Arachidonic acid is an essential fatty acid and a major constituent of biomembranes.
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- Reinheit: 99.21%
- CAS. Nr.: 69254-37-1
- Formel: C20H24D8O2
- Molecular Weight:312.52
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Speicherung:
Solution, -20°C, 2 years
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Biologische Aktivität
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Chemical Information
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Publications Citing Use of MedChemExpress (MCE) Arachidonic acid-d8
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Biologische Aktivität
Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Chemical Information
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CAS. Nr. 69254-37-1
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Unlabeled Cas 506-32-1
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Appearance Liquid
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Molecular Weight 312.52
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Formel C20H24D8O2
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Color Colorless to light yellow
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SMILES
CCCCC/C([2H])=C([2H])\C/C([2H])=C([2H])\C/C([2H])=C([2H])\C/C([2H])=C([2H])\CCCC(O)=O
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Synonyms
Immunocytophyt-d8
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Solution, -20°C, 2 years
Publications (5)
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Journal Impact Factor
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Most Recent
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Cell Rep Med
2023 Jun 20;4(6):101061. PMID: 37267943 -
Phytomedicine
Mulberry (Morus alba l.) leaf improves arachidonic acid metabolism disorder in chronic obstructive pulmonary disease. [Abstract]2025 Nov 25:148:157392. PMID: 41101074 -
Biochem Pharmacol
Sleep deprivation exacerbates experimental colitis via down-regulating the clock gene Per2. [Abstract]2025 Aug 18;242(Pt 2):117224. PMID: 40834931 -
J Chromatogr B Analyt Technol Biomed Life Sci
UPLC-MS/MS-based targeted analysis of human serum revealed that aberrant arachidonic acid metabolism may contribute to the pathogenesis of type 2 diabetes mellitus. [Abstract]2026 Jan 15:1269:124871. PMID: 41308335 -
Reinheit & Dokumentation
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Data Sheet (274 KB)
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SDS (605 KB)
- English - EN (605 KB)
- Français - FR (605 KB)
- Deutsch - DE (605 KB)
- Norwegian - NO (605 KB)
- Español - ES (605 KB)
- Swedish - SV (605 KB)
- Italian - IT (605 KB)
- Korean - KR (605 KB)
- Portuguese - PT (605 KB)
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Handling Instructions (2659 KB)
Verweise
[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [Content Brief]
[2]. Tateishi N, et al. Dietary supplementation with arachidonic acid increases arachidonic acid content in paw, but does not affect arthritis severity or prostaglandin E2 content in rat adjuvant-induced arthritis model. Lipids Health Dis. 2015 Jan 16;14:3. [Content Brief]
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
Arachidonic acid-d8 Related Classifications
HY-109590S Related Classifications
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