Dextromilnacipran hydrochloride
Dextromilnacipran ((1R,2S)-Milnacipran; F2696) hydrochloride is an orally active Serotonin (HY-B1473A)/Noradrenaline (HY-13715) transporter inhibitor. Dextromilnacipran hydrochloride inhibits Serotonin and Noradrenaline reuptake. Dextromilnacipran hydrochloride can be used for the research of depression, fibromyalgia.
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- CAS. Nr.: 175131-61-0
- Formel: C15H23ClN2O
- Molecular Weight:282.81
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Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biologische Aktivität
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| HEK293 | IC50 |
0.05 μM
Compound: Milnacipran
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Inhibition of the Norepinephrine transporter (NET, SLC6A2) as assessed by GPCR-mediated changes in cell morphology using the impedance-based transporter activity through receptor activation (TRACT) assay in HEK-293 JumpIN-SLC6A2 cells (PubChem AID: 174586
Inhibition of the Norepinephrine transporter (NET, SLC6A2) as assessed by GPCR-mediated changes in cell morphology using the impedance-based transporter activity through receptor activation (TRACT) assay in HEK-293 JumpIN-SLC6A2 cells (PubChem AID: 174586
|
[PMID: 34112854] |
Chemical Information
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CAS. Nr. 175131-61-0
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Molecular Weight 282.81
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Formel C15H23ClN2O
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SMILES
CCN(CC)C([C@@]1(C2=CC=CC=C2)[C@H](C1)CN)=O.Cl
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Synonyms
(1R,2S)-Milnacipran hydrochloride; F2696 hydrochloride
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation
Verweise
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)