LY-466195
LY-466195 is a selective and competitive GLUK5 receptor antagonist. LY-466195 antagonizes Kainate-induced currents with an IC50 value of 0.045 μM in rat dorsal root ganglion neurons. In HEK293 cells transfected with GLUK5, GLUK2/GLUK5, or GLUK5/GLUK66 receptors, LY466195 produces IC50 values of 0.08 μM, 0.34 μM, and 0.07 μM, respectively.
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- CAS. Nr.: 317844-33-0
- Formel: C16H24F2N2O4
- Molecular Weight:346.37
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Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biologische Aktivität
Chemical Information
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CAS. Nr. 317844-33-0
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Molecular Weight 346.37
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Formel C16H24F2N2O4
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SMILES
O=C([C@H]1NC[C@]2([H])CC[C@H](CN3[C@H](C(O)=O)CC(F)(F)C3)C[C@]2([H])C1)O
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation
Verweise
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
LY-466195 Related Classifications
HY-19858 Related Classifications
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