S-Diclofenac (Standard)
S-Diclofenac (Standard) is the analytical standard of S-Diclofenac. This product is intended for research and analytical applications. S-Diclofenac (ACS 15) is a hybrid molecule of an H2S donor and the NSAID diclofenac. S-Diclofenac activates the p53 signaling pathway, and inhibits the activation of JNK. S-Diclofenac exhibits antioxidant and anti-inflammatory activities.
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- Reinheit: 98%
- CAS. Nr.: 912758-00-0
- Formel: C23H15Cl2NO2S3
- Molecular Weight:504.47
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Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Product Information
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Chemical Information
- Reinheit & Dokumentation
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Help & FAQs
Product Information
The compound is the grade of analytical standard, which is the reference standard supplied assay. It is commonly used in qualitative, quantitative and methodological research experiments in HPLC, GC and MS.
Chemical Information
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CAS. Nr. 912758-00-0
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Molecular Weight 504.47
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Formel C23H15Cl2NO2S3
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SMILES
O=C(CC1=C(NC2=C(Cl)C=CC=C2Cl)C=CC=C1)OC3=CC=C(C(SS4)=CC4=S)C=C3
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Synonyms
ACS 15 (Standard); ATB-337 (Standard)
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation
Verweise
[1]. Wallace JL, et al. Gastrointestinal safety and anti-inflammatory effects of a hydrogen sulfide-releasing diclofenac derivative in the rat. Gastroenterology. 2007 Jan;132(1):261-71. [Content Brief]
[2]. Sidhapuriwala J, et al., Effect of S-diclofenac, a novel hydrogen sulfide releasing derivative, on carrageenan-induced hindpaw oedema formation in the rat. Eur J Pharmacol. 2007 Aug 13;569(1-2):149-54. [Content Brief]
[3]. Zhang H, et al., S-diclofenac protects against doxorubicin-induced cardiomyopathy in mice via ameliorating cardiac gap junction remodeling. PLoS One. 2011;6(10):e26441 [Content Brief]
[4]. Baskar R, et al., Effect of S-diclofenac, a novel hydrogen sulfide releasing derivative inhibit rat vascular smooth muscle cell proliferation. Eur J Pharmacol. 2008 Oct 10;594(1-3):1-8. [Content Brief]
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
S-Diclofenac (Standard) Related Classifications
HY-15035R Related Classifications
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