WZ-2-033
WZ-2-033 is a potent STAT3 inhibitor. WZ-2-033 inhibits MDA-MB-231, HCC70, and MDA-MB231-4175 cells proliferation, colony survival, migration, and invasion with IC50s of 0.7, 1.3, and 1.3 μM, respectively.
Nur für Forschungszwecke. Wir verkaufen nicht an Patienten.
- CAS. Nr.: 2416196-47-7
- Formel: C25H18F3N3O4S
- Molecular Weight:513.49
-
Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biologische Aktivität
|
Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| A549 | IC50 |
0.4 μM
Compound: 50
|
Antiproliferative activity against human A549 cells
Antiproliferative activity against human A549 cells
|
[PMID: 34000483] |
| MDA-MB-231 | IC50 |
0.7 μM
Compound: 50
|
Antiproliferative activity against human MDA-MB-231 cells
Antiproliferative activity against human MDA-MB-231 cells
|
[PMID: 34000483] |
| MGC-803 | IC50 |
0.4 μM
Compound: 50
|
Antiproliferative activity against human MGC-803 cells
Antiproliferative activity against human MGC-803 cells
|
[PMID: 34000483] |
Chemical Information
-
CAS. Nr. 2416196-47-7
-
Molecular Weight 513.49
-
Formel C25H18F3N3O4S
-
SMILES
O=C(CC1=C(C2=CC=C(C(F)(F)F)C=C2)N=C3C=C(C=CN31)OC)NC4=CC5=C(C=CS(=O)5=O)C=C4
-
Versand
Room temperature in continental US; may vary elsewhere.
-
Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation
Verweise
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)