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Cat. No.: HY-19841

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AVE-5997

AVE-5997 is a selective b>D₃ antagonist. AVE-5997 antagonizes MK-801 (HY-15084B)-induced hyperactivity. AVE-5997 can be used in the research of schizophrenia.

For research use only. We do not sell to patients.

CAS No.: 452917-21-4
Formula: C₂₅H₂₉F₃N₄OS
Molecular Weight:490.58

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (264 KB)

AVE-5997 Chemical Structure

CAS No.: 452917-21-4

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Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- IC₅₀ & Target
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

Description

AVE-5997 is a selective b>D₃ antagonist. AVE-5997 antagonizes MK-801 (HY-15084B)-induced hyperactivity. AVE-5997 can be used in the research of schizophrenia^[1].

IC₅₀ & Target^[1]

D₃ Receptor

All Dopamine Receptor Isoforms :

Chemical Information

CAS No. 452917-21-4
Molecular Weight 490.58
Formula C₂₅H₂₉F₃N₄OS
SMILES

O=C(NCCCCN1CCN(C2=CSC3=CC(C(F)(F)F)=CC=C32)CC1)NC4=CC=C(C)C=C4
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (264 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Zhang M, et al. Effect of dopamine D3 antagonists on PPI in DBA/2J mice or PPI deficit induced by neonatal ventral hippocampal lesions in rats. Neuropsychopharmacology. 2006 Jul;31(7):1382-92. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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Biological Activity
- Description
- IC₅₀ & Target
Chemical Information
Purity & Documentation
References

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AVE-5997

All Dopamine Receptor Isoforms

Biological Activity

Chemical Information

Purity & Documentation

References

Calculators

Help & FAQs

AVE-5997 Related Classifications

HY-19841 Related Classifications