L-Leucine-d3
Based on 3 publication(s) in Google Scholar
L-Leucine-d3 is the deuterium labeled L-Leucine. L-Leucine is an essential branched-chain amino acid (BCAA), which activates the mTOR signaling pathway.
For research use only. We do not sell to patients.
- Purity: 99.98%
- CAS No.: 87828-86-2
- Formula: C6H10D3NO2
- Molecular Weight:134.19
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Storage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
Publications Citing Use of MedChemExpress (MCE) L-Leucine-d3
MoreAll Endogenous Metabolite Isoforms
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Biological Activity
Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Chemical Information
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CAS No. 87828-86-2
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Unlabeled Cas 61-90-5
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Appearance Solid
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Molecular Weight 134.19
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Formula C6H10D3NO2
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Color White to off-white
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SMILES
[2H]C([2H])([2H])C(C)C[C@H](N)C(O)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Publications (3)
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Journal Impact Factor
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Most Recent
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Food Res Int
Changing trends of non-volatile metabolites during industrial broad bean paste production via untargeted metabolomics. [Abstract]2026 Jan;223(Pt 1):117926. PMID: 41352829 -
Breast Cancer Res
Serum metabolomic profiling for predicting therapeutic response and toxicity in breast cancer neoadjuvant chemotherapy: a retrospective longitudinal study. [Abstract]2025 Jan 6;27(1):2. PMID: 39762945 -
Solvent & Solubility
H2O : ≥ 10 mg/mL (74.52 mM)
* "≥" means soluble, but saturation unknown.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (271 KB)
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SDS (394 KB)
- English - EN (394 KB)
- Français - FR (394 KB)
- Deutsch - DE (394 KB)
- Norwegian - NO (394 KB)
- Español - ES (394 KB)
- Swedish - SV (394 KB)
- Italian - IT (394 KB)
- Portuguese - PT (394 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| H2O | 1 mM | 7.4521 mL | 37.2606 mL | 74.5212 mL | 186.3030 mL |
| 5 mM | 1.4904 mL | 7.4521 mL | 14.9042 mL | 37.2606 mL | |
| 10 mM | 0.7452 mL | 3.7261 mL | 7.4521 mL | 18.6303 mL | |
| 15 mM | 0.4968 mL | 2.4840 mL | 4.9681 mL | 12.4202 mL | |
| 20 mM | 0.3726 mL | 1.8630 mL | 3.7261 mL | 9.3151 mL | |
| 25 mM | 0.2981 mL | 1.4904 mL | 2.9808 mL | 7.4521 mL | |
| 30 mM | 0.2484 mL | 1.2420 mL | 2.4840 mL | 6.2101 mL | |
| 40 mM | 0.1863 mL | 0.9315 mL | 1.8630 mL | 4.6576 mL | |
| 50 mM | 0.1490 mL | 0.7452 mL | 1.4904 mL | 3.7261 mL | |
| 60 mM | 0.1242 mL | 0.6210 mL | 1.2420 mL | 3.1050 mL |
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
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