STING-IN-11
Based on 1 Customer Validation
STING-IN-11 (Compound 42) is an orally active STING inhibitor with an IC50 of 37.8 nM. STING-IN-11 can block the palmitoylation of the STING protein and STING downstream signaling, and inhibit STING-mediated inflammation. STING-IN-11 has good in vivo safety and can be used for the research of STING-related inflammatory and autoimmune diseases.
For research use only. We do not sell to patients.
- Purity: 98.65%
- CAS No.: 2925028-15-3
- Formula: C21H20ClF2N3O
- Molecular Weight:403.85
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Storage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
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Biological Activity
Chemical Information
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CAS No. 2925028-15-3
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Appearance Solid
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Molecular Weight 403.85
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Formula C21H20ClF2N3O
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Color White to off-white
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SMILES
O=C(NC1=CNC2=C1C=C(Cl)C=C2)NC3=CC=C(C4CCC(F)(CC4)F)C=C3
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
DMSO : 100 mg/mL (247.62 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (270 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
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| DMSO | 1 mM | 2.4762 mL | 12.3808 mL | 24.7617 mL | 61.9042 mL |
| 5 mM | 0.4952 mL | 2.4762 mL | 4.9523 mL | 12.3808 mL | |
| 10 mM | 0.2476 mL | 1.2381 mL | 2.4762 mL | 6.1904 mL | |
| 15 mM | 0.1651 mL | 0.8254 mL | 1.6508 mL | 4.1269 mL | |
| 20 mM | 0.1238 mL | 0.6190 mL | 1.2381 mL | 3.0952 mL | |
| 25 mM | 0.0990 mL | 0.4952 mL | 0.9905 mL | 2.4762 mL | |
| 30 mM | 0.0825 mL | 0.4127 mL | 0.8254 mL | 2.0635 mL | |
| 40 mM | 0.0619 mL | 0.3095 mL | 0.6190 mL | 1.5476 mL | |
| 50 mM | 0.0495 mL | 0.2476 mL | 0.4952 mL | 1.2381 mL | |
| 60 mM | 0.0413 mL | 0.2063 mL | 0.4127 mL | 1.0317 mL | |
| 80 mM | 0.0310 mL | 0.1548 mL | 0.3095 mL | 0.7738 mL | |
| 100 mM | 0.0248 mL | 0.1238 mL | 0.2476 mL | 0.6190 mL |
STING-IN-11 Related Classifications
HY-170949 Related Classifications
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