2925028-15-3
2925028-15-3
Chemical Structure
STING-IN-11
- CAS No.: 2925028-15-3
- Formula:C21H20ClF2N3O
- Molecular Weight:403.85
SMILES: O=C(NC1=CNC2=C1C=C(Cl)C=C2)NC3=CC=C(C4CCC(F)(CC4)F)C=C3
Biological Activity: STING-IN-11 (Compound 42) is an orally active STING inhibitor with an IC50 of 37.8 nM. STING-IN-11 can block the palmitoylation of the STING protein and STING downstream signaling, and inhibit STING-mediated inflammation. STING-IN-11 has good in vivo safety and can be used for the research of STING-related inflammatory and autoimmune diseases[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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STING-IN-11 | 98.65% | STING-IN-11 (Compound 42) is an orally active STING inhibitor with an IC50 of 37.8 nM. STING-IN-11 can block the palmitoylation of the STING protein and STING downstream signaling, and inhibit STING-mediated inflammation. STING-IN-11 has good in vivo safety and can be used for the research of STING-related inflammatory and autoimmune diseases. | ||||||||||||||||||||
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References
Keywords
