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Cat. No.: HY-113443

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12(S)-HPETE

12(S)-HPETE is a 12-hydroxyeicosatetraenoic acid. 12(S)-HPETE has the function of regulating vascular tone. 12(S)-HPETE induces the expression of c-Fos and c-Jun protein and increases activating protein 1 (AP-1) activity in vascular smooth muscle cells.12(S)-HPETE may play a physiological role in vasomotor regulation through endothelium itself and crosstalk between blood cells and endothelium. 12(S)-HPETE can be used in the study of cerebrovascular tension.

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CAS No.: 71774-10-2
Formule: C₂₀H₃₂O₄
Masse moléculaire:336.47

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Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (261 KB)

12(S)-HPETE Chemical Structure

CAS No.: 71774-10-2

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Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

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Description

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Chemical Information

CAS No. 71774-10-2
Masse moléculaire 336.47
Formule C₂₀H₃₂O₄
SMILES

CCCCC/C=C\C[C@H](OO)/C=C/C=C\C/C=C\CCCC(O)=O
Initial Source
- Microorganisms
Livraison

Room temperature in continental US; may vary elsewhere.
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Please store the product under the recommended conditions in the Certificate of Analysis.

Pureté et documentation

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Pureté: 99.98%

Assay: 99.98%

ee.: 99.98%

Fiche technique (261 KB)
SDS (252 KB)
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COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instruction de manipulation (2659 KB)

Références

[1]. Nishiyama M, et al. Endothelium is required for 12-hydroperoxyeicosatetraenoic acid-induced vasoconstriction. Eur J Pharmacol. 1998 Jan 2;341(1):57-63. [Content Brief]

[2]. Rao GN, et al. Role of hydroperoxyeicosatetraenoic acids in oxidative stress-induced activating protein 1 (AP-1) activity. J Biol Chem. 1996 Nov 1;271(44):27760-4. [Content Brief]

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12(S)-HPETE

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Activité biologique

Chemical Information

Pureté et documentation

Références

Calculators

Help & FAQs

12(S)-HPETE Related Classifications

HY-113443 Related Classifications