Afabicin diolamine
Afabicin diolamine (Debio 1450 diolamine) is the proagent of Debio1452 (HY-16911), specifically targeting staphylococci without significant activity against other Gram-positive or Gram-negative species. Debio1452 is an inhibitor FabI, an enzyme critical to fatty acid biosynthesis in staphylococci.
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- CAS No.: 1518800-36-6
- Formule: C27H38N5O9P
- Masse moléculaire:607.59
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Activité biologique
| NCT Number | Sponsor | Condition | Start Date |
Phase
|
|---|---|---|---|---|
| NCT01329991 | Plexxikon| | 2011-05 | PHASE1 |
Chemical Information
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CAS No. 1518800-36-6
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Masse moléculaire 607.59
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Formule C27H38N5O9P
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SMILES
OCCN.O=P(O)(O)OCN1C2=NC=C(/C=C/C(N(C)CC3=C(C)C4=CC=CC=C4O3)=O)C=C2CCC1=O.OCCN
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Synonyms
Debio 1450 diolamine; AFN-1720 diolamine
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)