B-Raf IN 6
B-Raf IN 6 (compound 2c) is a potent inhibitor of protein kinase B-Raf with an IC50 of 1.7 nM. B-Raf IN 6 is devoid of binding to the secondary target PXR and resists rapid metabolism. B-Raf IN 6 has the potential for the research of cancer disease.
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- CAS No.: 2648698-34-2
- Formule: C24H21F3N6O2S2
- Masse moléculaire:546.59
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Activité biologique
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Chemical Information
- Pureté et documentation
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Help & FAQs
Activité biologique
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| A-375 | IC50 |
5.12 nM
Compound: 2c
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Antiproliferative activity against human A-375 cells assessed as inhibition of cell growth measured after 5 days by MTT assay
Antiproliferative activity against human A-375 cells assessed as inhibition of cell growth measured after 5 days by MTT assay
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[PMID: 34958586] |
Chemical Information
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CAS No. 2648698-34-2
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Masse moléculaire 546.59
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Formule C24H21F3N6O2S2
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SMILES
O=S(C1=CC(F)=CC=C1F)(NC2=CC=CC(C3=C(C4=NC(N)=NC=C4)SC(C5NCCCC5)=N3)=C2F)=O
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
B-Raf IN 6 Related Classifications
HY-142830 Related Classifications
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