Cavrotolimod
Cavrotolimod is an immunostimulatory spherical nucleic acid (SNA) modified with type B CpG oligonucleotides designed to agonize TLR9 and elicit immune responses useful in oncology applications.
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- CAS No.: 2378664-12-9
- Formule: C300H423N71O161P26S23
- Masse moléculaire:9142.88
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Activité biologique
Chemical Information
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CAS No. 2378664-12-9
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Masse moléculaire 9142.88
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Formule C300H423N71O161P26S23
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SMILES
[Cavrotolimod]
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Synonyms
AST-008
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
[1]. Daniel WL, Lorch U, Mix S, Bexon AS. A first-in-human phase 1 study of cavrotolimod, a TLR9 agonist spherical nucleic acid, in healthy participants: Evidence of immune activation. Front Immunol. 2022;13:1073777. [Content Brief]
[2]. Rubatto M, Sciamarrelli N, Borriello S, et al. Classic and new strategies for the treatment of advanced melanoma and non-melanoma skin cancer. Front Med (Lausanne). 2023;9:959289. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)