COX-2-IN-20
COX-2-IN-20 (Compound 5d) is a selective and orally active COX-2 inhibitor with an IC50 of 17.9 nM. COX-2-IN-20 shows anti-inflammatory activity.
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- CAS No.: 2529451-43-0
- Formule: C11H9ClFN3O2
- Masse moléculaire:269.66
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Activité biologique
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Chemical Information
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Activité biologique
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COX-2 17.9 nM (IC50) |
COX-1 19.3 μM (IC50) |
COX-2-IN-20 (Compound 5d) shows potential anti-inflammatory activity on NO inhibition in LPS-induced RAW 264.7 cell with an IC50 of 2.87 μM[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 2529451-43-0
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Masse moléculaire 269.66
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Formule C11H9ClFN3O2
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SMILES
O=C(C1=NN(C2=CC=C(F)C=C2)C(CCl)=N1)OC
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
COX-2-IN-20 Related Classifications
HY-147809 Related Classifications
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