COX-2-IN-23
COX-2-IN-23 (compound 9a) is a selective COX-2 inhibitor with IC50 values of 0.28 and 20.14 μM for COX-2 and COX-1. COX-2-IN-23 has anti-inflammatory activity and low ulcerogenic activity.
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- CAS No.: 2417995-08-3
- Formule: C24H25N5O3S2
- Masse moléculaire:495.62
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Activité biologique
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Chemical Information
- Pureté et documentation
- Références
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Help & FAQs
Activité biologique
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COX-2 0.28 μM (IC50) |
COX-1 20.14 μM (IC50) |
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Animal Model:Mature male albino rats[1]
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Dosage:9 mg/kg
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Administration:Intraperitoneal injection; 0, 1, 2, 3 and 4 hours.
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Result:Had similar ulcerogenic activity to celecoxib.
Chemical Information
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CAS No. 2417995-08-3
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Masse moléculaire 495.62
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Formule C24H25N5O3S2
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SMILES
O=S(C1=CC(C(N2C3=CC=CC=C3)=NNC2=S)=CC(NCCCC)=C1OC4=CC=CC=C4)(N)=O
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
COX-2-IN-23 Related Classifications
HY-147961 Related Classifications
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