COX-2-IN-24
COX-2-IN-24 is an orally active inhibitor of COX-2 with IC50 value of 0.17 μM, shows anti-inflammatory and low ulcerogenic activities.
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- CAS No.: 2417995-10-7
- Formule: C24H24BrN5O3S2
- Masse moléculaire:574.51
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Activité biologique
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Chemical Information
- Pureté et documentation
- Références
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Help & FAQs
Activité biologique
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COX-2 0.17 μM (IC50) |
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Animal Model:Mature male albino rats[1]
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Dosage:9mg/100g
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Administration:Intraperitoneal injection; 9mg/100g; once an hour; 4 hours
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Result:Exhibited a promising anti-inflammatory activity in the carrageenan-induced rat paw edema model.
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Animal Model:Mature male albino rats[1]
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Dosage:9mg/100g
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Administration:Oral gavage; 9mg/100g; once a day; 3 days
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Result:Exhibited low ulcerogenic activity in the received 1% gum acacia (suspending vehicle) orally male albino rats model.
Chemical Information
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CAS No. 2417995-10-7
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Masse moléculaire 574.51
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Formule C24H24BrN5O3S2
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SMILES
O=S(C1=CC(C(N2C3=CC=C(Br)C=C3)=NNC2=S)=CC(NCCCC)=C1OC4=CC=CC=C4)(N)=O
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
COX-2-IN-24 Related Classifications
HY-147963 Related Classifications
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