DSPE-PEG2000-WYRGRL
Based on 1 Customer Validation
DSPE-PEG2000-WYRGRL is a PEG compound which composed of DSPE and a cartilage-targeting peptide (WYRGRL). WYRGRL is a collagen II-targeting peptide that can bind to collagen II α1. DSPE-PEG2000-WYRGRL can be used for drug delivery.
Nos produits utilisent uniquement pour la recherche. Nous ne vendons pas aux patients.
- Pureté: 95.0%
- Masse moléculaire:2000 (Average)
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Activité biologique
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Collagen II |
WYRGRL can specifically bind to Collagen II of articular cartilage[1].
WYRGRL exhibits cartilage-targeting activity[2].
The strategy of encapsulating Lecithin (HY-B2235), Cholesterol (HY-N0322), DSPE-PEG2000-WYRGRL, and Urolithin A (HY-100599) into HAMA microspheres using microfluidic and photopolymerization techniques may alleviate cartilage degeneration by targeting chondrocytes and activating mitochondrial autophagy[2].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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Appearance Solid
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Masse moléculaire 2000 (Average)
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Color White to off-white
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SMILES
[Mal-Cys-WYRGRL]C(CCOCCOC(NCCOP(OC[C@](COC(CCCCCCCCCCCCCCCCC)=O)([H])OC(CCCCCCCCCCCCCCCCC)=O)(O)=O)=O)=O.[n]
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Solvant et solubilité
DMSO : ≥ 100 mg/mL
* "≥" means soluble, but saturation unknown.
Pureté et documentation
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Fiche technique (268 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Instruction de manipulation (2659 KB)
Références
[1]. Kai Ren, et al. Zwitterionic polymer modified xanthan gum with collagen II-binding capability for lubrication improvement and ROS scavenging. Carbohydr Polym. 2021 Nov 15:274:118672. [Content Brief]
[2]. Mitsou E, Klein J. Liposome-Based Interventions in Knee Osteoarthritis. Small. 2025 Apr;21(17):e2410060. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)