Profadol hydrochloride
Profadol (CI-572) hydrochloride is a potent analgesic agent. Profadol is a µ-opioid receptor (MOR) agonist. Profadol hydrochloride activates the γ-aminobutyric acid (GABA) receptors and inhibits the N-methyl-D-aspartate (NMDA) receptor. Profadol increases the mRNA and protein expression of MOR.
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- CAS No.: 2324-94-9
- Formule: C14H22ClNO
- Masse moléculaire:255.78
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Activité biologique
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Chemical Information
- Pureté et documentation
- Références
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Activité biologique
Chemical Information
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CAS No. 2324-94-9
-
Masse moléculaire 255.78
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Formule C14H22ClNO
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SMILES
OC1=CC=CC(C2(CCC)CN(CC2)C)=C1.Cl
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Synonyms
CI-572 hydrochloride
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
[1]. Beaver WT, et al. A comparison of the analgesic effects of profadol and morphine in patients with cancer. Clin Pharmacol Ther. 1969 May-Jun;10(3):314-9. [Content Brief]
[2]. Li Z, et al. Propofol increases µ-opioid receptor expression in SH-SY5Y human neuroblastoma cells. Mol Med Rep. 2012 Dec;6(6):1333-6. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Profadol hydrochloride Related Classifications
HY-105627A Related Classifications
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