Pulchinenoside K
Pulchinenoside K (Compound 4) is a triterpenoid saponin. Pulchinenoside K can be isolated from the roots of *Pulsatilla koreana*. Pulchinenoside K inhibits NO production. Pulchinenoside K can be used for the research of inflammatory diseases.
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- CAS No.: 1257378-28-1
- Formule: C65H106O30
- Masse moléculaire:1367.53
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
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Activité biologique
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Chemical Information
- Pureté et documentation
- Références
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Help & FAQs
Activité biologique
Pulchinenoside K (1-100 μM; 1 h pre-treatment + 24 h LPS co-incubation) significantly inhibits LPS-induced NO production in RAW 264.7 cells at concentrations of 1 μM and 10 μM, and a decrease in cell viability is observed at all tested concentrations[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Cell Line:RAW 264.7 macrophage cells
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Concentration:1 μM, 10 μM, 100 μM
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Incubation Time:25 h (total: 1 h pre-treatment + 24 h LPS co-incubation)
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Result:Reduced relative NO production to 79.1% with a cell viability of 87.5% at 1 μM (significantly reduced compared to LPS-only control, p < 0.05).
Reduced relative NO production to 63.1% with a cell viability of 74.5% at 10 μM (significantly reduced, p < 0.01).
Reduced relative NO production to 79.1% with a cell viability of 51.5% at 100 μM.
Chemical Information
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CAS No. 1257378-28-1
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Masse moléculaire 1367.53
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Formule C65H106O30
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SMILES
C(O[C@@H]1O[C@H](CO[C@@H]2O[C@H](CO)[C@@H](O[C@H]3[C@H](O)[C@H](O)[C@@H](O)[C@H](C)O3)[C@H](O)[C@H]2O)[C@@H](O)[C@H](O)[C@H]1O)(=O)[C@]45[C@@]([C@@]6([C@@](C)(CC4)[C@@]7(C)[C@](CC6)([C@]8(C)[C@@](CC7)(C(C)(C)[C@@H](O[C@H]9[C@H](O[C@H]%10[C@H](O)[C@H](O)[C@@H](O)[C@H](C)O%10)[C@@H](O)[C@@H](O[C@@H]%11O[C@H](CO)[C@@H](O)[C@H](O)[C@H]%11O)CO9)CC8)[H])[H])[H])([C@H](C(C)=C)CC5)[H]
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Structure Classification
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Initial Source
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Pulchinenoside K Related Classifications
HY-N19122 Related Classifications
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