RAF mutant-IN-1
RAF mutant-IN-1 is a RAF kinase inhibitor, extracted from patent WO2019107987A1, with IC50 values of 21 nM, 30 nM and 392 nM for C-RAF 340D/Y341D, B-RAFV600E and B-RAFWT, respectively.
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- CAS No.: 2340020-82-6
- Formule: C23H18Cl3FN6O2S
- Masse moléculaire:567.85
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Activité biologique
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Chemical Information
- Pureté et documentation
- Références
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Help & FAQs
Activité biologique
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C-RAF 340D/Y341D 21 nM (IC50) |
B-RafV600E 30 nM (IC50) |
BRAFWT 392 nM (IC50) |
Chemical Information
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CAS No. 2340020-82-6
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Masse moléculaire 567.85
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Formule C23H18Cl3FN6O2S
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SMILES
O=C(C1=CSC2=C(N)N=CN=C21)NC3=C(C)C=CC4=C3C=CN=C4NC5=CC=C(O)C(Cl)=C5F.[H]Cl.[H]Cl
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
RAF mutant-IN-1 Related Classifications
HY-126298 Related Classifications
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