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Cat. No.: HY-B0964A

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Riboflavin phosphate

(Synonyms: Riboflavine phosphate; Riboflavin 5'-phosphate; Riboflavine 5'-phosphate)

2 Cited Publications

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Based on 2 publication(s) in Google Scholar

Riboflavine phosphate is a derivative of Riboflavin (vitamin B2) which is an essential nutrient for animals. Riboflavin phosphate can be used for the research of progressive keratoconus, corneal ectasia and irregular astigmatism. Riboflavine phosphate is a very effective NAD⁺-recycling agent.

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CAS No.: 146-17-8
Formule: C₁₇H₂₁N₄O₉P
Masse moléculaire:456.34

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Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (274 KB)

Riboflavin phosphate Chemical Structure

CAS No.: 146-17-8

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Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Activité biologique
- Description
- IC₅₀ & Target
- In Vitro
Chemical Information
Publications (2)
Pureté et documentation
Références
Calculators
Help & FAQs
Classifications
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Activité biologique

Description

Riboflavine phosphate is a derivative of Riboflavin (vitamin B2) which is an essential nutrient for animals. Riboflavin phosphate can be used for the research of progressive keratoconus, corneal ectasia and irregular astigmatism^[1]^[2]. Riboflavine phosphate is a very effective NAD⁺-recycling agent^[3].

IC₅₀ & Target

Human Endogenous Metabolite

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In Vitro

Riboflavine phosphate (Flavin mononucleotide) is clearly a very effective NAD⁺-recycling agent with good yields of the cyclohexanone product accompanied by high levels of NAP turnover being achieved routinely^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS No. 146-17-8
Masse moléculaire 456.34
Formule C₁₇H₂₁N₄O₉P
SMILES

CC1=CC2=C(C=C1C)N=C(C(N2C[C@@H]([C@@H]([C@@H](COP(O)(O)=O)O)O)O)=N3)C(NC3=O)=O
Synonyms

Riboflavine phosphate; Riboflavin 5'-phosphate; Riboflavine 5'-phosphate
Structure Classification
- Ketones, Aldehydes, Acids
Initial Source
- Endogenous metabolite
Livraison

Room temperature in continental US; may vary elsewhere.
Stockage

Please store the product under the recommended conditions in the Certificate of Analysis.

Publications (2)

All Cell Proliferation/Viability AssayCell Migration/Invasion AssayIn Vivo Efficacy Study

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Journal Impact Factor

Signal Transduct Target Ther

Short-chain acyl-CoA dehydrogenase initiates mtDNA demethylation and leakage to fuel antitumor immunity in colorectal cancer. [Abstract]

2026 Mar 26;11(1):113. PMID: 41888107
Nat Commun

FAD synthase confers ferroptosis resistance and restrains CD8+ T cell recruitment in hepatocellular carcinoma. [Abstract]

2025 Oct 29;16(1):9547. PMID: 41162372

Riboflavin phosphate purchased from MedChemExpress. Usage Cited in: Nat Commun. 2025 Oct 29;16(1):9547. [Abstract]

Hep3B and HCCLM3 cells treated with Riboflavin (VB2; 10 µM), Riboflavin phosphate sodium (FMN; 10 µM), Flavin adenine dinucleotide (FAD; 10 µM), or PBS (Ctrl) for 48 h, followed by CCK-8 assay.

Riboflavin phosphate purchased from MedChemExpress. Usage Cited in: Nat Commun. 2025 Oct 29;16(1):9547. [Abstract]

Riboflavin phosphate sodium (FMN; Lumiflavin) (10 μM; 48 h) increased migration of HCCLM3 cells.

Riboflavin phosphate purchased from MedChemExpress. Usage Cited in: Nat Commun. 2025 Oct 29;16(1):9547. [Abstract]

Riboflavin phosphate sodium (FMN) (50 mg/kg; i.t.; once daily for 17 d) accelerated tumor growth and increased tumor weight in Rag1^⁻/⁻ mice.

Pureté et documentation

Select Batch:

Pureté: 99.98%

Assay: 99.98%

ee.: 99.98%

Fiche technique (274 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instruction de manipulation (2659 KB)

Références

[1]. J. Bryan Jones, et al. Nicotinamide coenzyme regeneration. Flavin mononucleotide (riboflavin phosphate) as an efficient, economical, and enzyme-compatible recycling agent. Can J Chem. 1976, 54(19): 2969-2973,

[2]. José Luis Revuelta, et al. Bioproduction of riboflavin: a bright yellow history. J Ind Microbiol Biotechnol. 2017 May;44(4-5):659-665. [Content Brief]

[3]. Carmine Ostacolo, et al. Enhancement of corneal permeation of riboflavin-5'-phosphate through vitamin E TPGS: a promising approach in corneal trans-epithelial cross linking treatment. Int J Pharm. 2013 Jan 20;440(2):148-53. [Content Brief]

Calculators

Calculateur de molarité

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Calculateur de dilution

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Keywords

Riboflavin phosphate

2 Cited Publications

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Activité biologique
- Description
- IC₅₀ & Target
- In Vitro
Chemical Information
Publications (2)
Pureté et documentation
Références

1/16
1/16

Riboflavin phosphate purchased from MedChemExpress. Usage Cited in: Nat Commun. 2025 Oct 29;16(1):9547. [Abstract]

Customer Validation
Hep3B and HCCLM3 cells treated with Riboflavin (VB2; 10 µM), Riboflavin phosphate sodium (FMN; 10 µM), Flavin adenine dinucleotide (FAD; 10 µM), or PBS (Ctrl) for 48 h, followed by CCK-8 assay.
1/16

Riboflavin phosphate purchased from MedChemExpress. Usage Cited in: Nat Commun. 2025 Oct 29;16(1):9547. [Abstract]

Customer Validation
Riboflavin phosphate sodium (FMN; Lumiflavin) (10 μM; 48 h) increased migration of HCCLM3 cells.
1/16

Riboflavin phosphate purchased from MedChemExpress. Usage Cited in: Nat Commun. 2025 Oct 29;16(1):9547. [Abstract]

Customer Validation
Riboflavin phosphate sodium (FMN) (50 mg/kg; i.t.; once daily for 17 d) accelerated tumor growth and increased tumor weight in Rag1^⁻/⁻ mice.

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Riboflavin phosphate

Publications Citing Use of MedChemExpress (MCE) Riboflavin phosphate

Voir tous les produits spécifiques à Isoform Endogenous Metabolite

Activité biologique

Chemical Information

Publications (2)

Pureté et documentation

Références

Calculators

Help & FAQs

Riboflavin phosphate Related Classifications

HY-B0964A Related Classifications