2. Metabolic Enzyme/Protease
  3. Endogenous Metabolite
  4. Riboflavin phosphate sodium

Riboflavin phosphate sodium  (Synonyms: Riboflavine phosphate sodium; Riboflavin 5'-phosphate sodium; Riboflavine 5'-phosphate sodium)

Cat. No.: HY-B0964 Purity: 93.36%
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Handling Instructions Technical Support

Riboflavin phosphate sodium (FMN-Na) is a derivative of Riboflavin (vitamin B2) which is an essential nutrient for animals. Riboflavin phosphate sodium can be used for the research of progressive keratoconus, corneal ectasia and irregular astigmatism. Riboflavine phosphate sodium is a very effective NAD+-recycling agent.

For research use only. We do not sell to patients.

CAS No. : 130-40-5

Size Price Stock Quantity
Solid + Solvent (Highly Recommended)
10 mM * 1 mL in Water
ready for reconstitution
 In-stock
Solution
10 mM * 1 mL in Water In-stock
Solid
100 mg In-stock
500 mg In-stock
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5 g   Get quote  

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This product is a controlled substance and not for sale in your territory.

Customer Review

Based on 2 publication(s) in Google Scholar

Other Forms of Riboflavin phosphate sodium:

Riboflavin phosphate sodium Related Antibodies

Top Publications Citing Use of Products
Cell Proliferation/Viability Assay
Cell Migration/Invasion Assay
In Vivo Efficacy Study

    Riboflavin phosphate sodium purchased from MedChemExpress. Usage Cited in: Nat Commun. 2025 Oct 29;16(1):9547.  [Abstract]

    Hep3B and HCCLM3 cells treated with Riboflavin (VB2; 10 µM), Riboflavin phosphate sodium (FMN; 10 µM), Flavin adenine dinucleotide (FAD; 10 µM), or PBS (Ctrl) for 48 h, followed by CCK-8 assay.

    Riboflavin phosphate sodium purchased from MedChemExpress. Usage Cited in: Nat Commun. 2025 Oct 29;16(1):9547.  [Abstract]

    Riboflavin phosphate sodium (FMN; Lumiflavin) (10 μM; 48 h) increased migration of HCCLM3 cells.

    Riboflavin phosphate sodium purchased from MedChemExpress. Usage Cited in: Nat Commun. 2025 Oct 29;16(1):9547.  [Abstract]

    Riboflavin phosphate sodium (FMN) (50 mg/kg; i.t.; once daily for 17 d) accelerated tumor growth and increased tumor weight in Rag1⁻/⁻ mice.

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    Human Endogenous Metabolite Microbial Metabolite

    • Biological Activity

    • Purity & Documentation

    • References

    • Customer Review

    Description

    Riboflavin phosphate sodium (FMN-Na) is a derivative of Riboflavin (vitamin B2) which is an essential nutrient for animals. Riboflavin phosphate sodium can be used for the research of progressive keratoconus, corneal ectasia and irregular astigmatism[1][2]. Riboflavine phosphate sodium is a very effective NAD+-recycling agent[3].

    IC50 & Target

    Human Endogenous Metabolite

     

    In Vitro

    Riboflavine phosphate sodium is clearly a very effective NAD+-recycling agent with good yields of the cyclohexanone product accompanied by high levels of NAP turnover being achieved routinely[3].

    MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

    Riboflavin phosphate sodium Related Antibodies
    Clinical Trial
    Molecular Weight

    478.33

    Formula

    C17H20N4NaO9P
    CAS No.
    Appearance

    Solid

    Color

    Light yellow to orange

    SMILES

    CC1=CC2=C(C=C1C)N=C(C(N2C[C@H](O)[C@H](O)[C@H](O)COP(O)(O[Na])=O)=N3)C(NC3=O)=O
    Structure Classification
    Initial Source
    Shipping

    Room temperature in continental US; may vary elsewhere.
    Storage

    4°C, protect from light, stored under nitrogen

    *In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)

    Solvent & Solubility
    In Vitro: 

    H2O : 50 mg/mL (104.53 mM; Need ultrasonic)

    DMSO : < 1 mg/mL (insoluble or slightly soluble)

    Preparing
    Stock Solutions
    Concentration Solvent Mass 1 mg 5 mg 10 mg
    1 mM 2.0906 mL 10.4530 mL 20.9061 mL
    5 mM 0.4181 mL 2.0906 mL 4.1812 mL
    View the Complete Stock Solution Preparation Table

    * Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
    Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

    * Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

    • Molarity Calculator

    • Dilution Calculator

    Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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    Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

    This equation is commonly abbreviated as: C1V1 = C2V2

    Concentration (start)

    C1

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    In Vivo:

    For the following dissolution methods, please prepare the working solution directly. It is recommended to prepare fresh solutions and use them promptly within a short period of time.
    The percentages shown for the solvents indicate their volumetric ratio in the final prepared solution. If precipitation or phase separation occurs during preparation, heat and/or sonication can be used to aid dissolution.

    • Protocol 1

      Add each solvent one by one:  PBS

      Solubility: 4.17 mg/mL (8.72 mM); Clear solution; Need ultrasonic and warming and heat to 60°C

    In Vivo Dissolution Calculator
    Please enter the basic information of animal experiments:

    Dosage

    mg/kg

    Animal weight
    (per animal)

    g

    Dosing volume
    (per animal)

    μL

    Number of animals

    Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
    Calculation results:
    Working solution concentration: mg/mL
    This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.
    The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).
    Purity & Documentation

    Purity: 93.36%

    SDS (394 KB)

    COA (256 KB) HNMR (292 KB) RP-HPLC (249 KB) MS (68 KB)

    Handling Instructions (2659 KB)
    References

    Complete Stock Solution Preparation Table

    * Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
    Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

    Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
    H2O 1 mM 2.0906 mL 10.4530 mL 20.9061 mL 52.2652 mL
    5 mM 0.4181 mL 2.0906 mL 4.1812 mL 10.4530 mL
    10 mM 0.2091 mL 1.0453 mL 2.0906 mL 5.2265 mL
    15 mM 0.1394 mL 0.6969 mL 1.3937 mL 3.4843 mL
    20 mM 0.1045 mL 0.5227 mL 1.0453 mL 2.6133 mL
    25 mM 0.0836 mL 0.4181 mL 0.8362 mL 2.0906 mL
    30 mM 0.0697 mL 0.3484 mL 0.6969 mL 1.7422 mL
    40 mM 0.0523 mL 0.2613 mL 0.5227 mL 1.3066 mL
    50 mM 0.0418 mL 0.2091 mL 0.4181 mL 1.0453 mL
    60 mM 0.0348 mL 0.1742 mL 0.3484 mL 0.8711 mL
    80 mM 0.0261 mL 0.1307 mL 0.2613 mL 0.6533 mL
    100 mM 0.0209 mL 0.1045 mL 0.2091 mL 0.5227 mL

    * Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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    Riboflavin phosphate sodium Related Classifications

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    • Do most proteins show cross-species activity?

      Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

    Keywords:

    Riboflavin phosphate130-40-5Riboflavine phosphateRiboflavin 5'-phosphateRiboflavine 5'-phosphateEndogenous MetaboliteRiboflavinnutrientkeratoconusInhibitorinhibitorinhibit

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