1. Metabolic Enzyme/Protease
  2. Endogenous Metabolite
  3. Riboflavin phosphate

Riboflavin phosphate  (Synonyms: Riboflavine phosphate; Riboflavin 5'-phosphate; Riboflavine 5'-phosphate)

Cat. No.: HY-B0964A
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Riboflavine phosphate is a derivative of Riboflavin (vitamin B2) which is an essential nutrient for animals. Riboflavin phosphate can be used for the research of progressive keratoconus, corneal ectasia and irregular astigmatism. Riboflavine phosphate is a very effective NAD+-recycling agent.

For research use only. We do not sell to patients.

CAS No. : 146-17-8

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Top Publications Citing Use of Products
Cell Proliferation/Viability Assay
Cell Migration/Invasion Assay
In Vivo Efficacy Study

    Riboflavin phosphate purchased from MedChemExpress. Usage Cited in: Nat Commun. 2025 Oct 29;16(1):9547.  [Abstract]

    Hep3B and HCCLM3 cells treated with Riboflavin (VB2; 10 µM), Riboflavin phosphate sodium (FMN; 10 µM), Flavin adenine dinucleotide (FAD; 10 µM), or PBS (Ctrl) for 48 h, followed by CCK-8 assay.

    Riboflavin phosphate purchased from MedChemExpress. Usage Cited in: Nat Commun. 2025 Oct 29;16(1):9547.  [Abstract]

    Riboflavin phosphate sodium (FMN; Lumiflavin) (10 μM; 48 h) increased migration of HCCLM3 cells.

    Riboflavin phosphate purchased from MedChemExpress. Usage Cited in: Nat Commun. 2025 Oct 29;16(1):9547.  [Abstract]

    Riboflavin phosphate sodium (FMN) (50 mg/kg; i.t.; once daily for 17 d) accelerated tumor growth and increased tumor weight in Rag1⁻/⁻ mice.

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    Description

    Riboflavine phosphate is a derivative of Riboflavin (vitamin B2) which is an essential nutrient for animals. Riboflavin phosphate can be used for the research of progressive keratoconus, corneal ectasia and irregular astigmatism[1][2]. Riboflavine phosphate is a very effective NAD+-recycling agent[3].

    IC50 & Target

    Human Endogenous Metabolite

     

    In Vitro

    Riboflavine phosphate (Flavin mononucleotide) is clearly a very effective NAD+-recycling agent with good yields of the cyclohexanone product accompanied by high levels of NAP turnover being achieved routinely[1].

    MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

    Molecular Weight

    456.34

    Formula

    C17H21N4O9P

    CAS No.
    SMILES

    CC1=CC2=C(C=C1C)N=C(C(N2C[C@@H]([C@@H]([C@@H](COP(O)(O)=O)O)O)O)=N3)C(NC3=O)=O

    Structure Classification
    Initial Source
    Shipping

    Room temperature in continental US; may vary elsewhere.

    Storage

    Please store the product under the recommended conditions in the Certificate of Analysis.

    Purity & Documentation
    References
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      Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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    Product Name:
    Riboflavin phosphate
    Cat. No.:
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